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Geometric mean titers (GMTs) of enzyme-linked immunosorbent assay of total immunoglobulin (Pan-Ig) antibodies to norovirus GI.1 and GII.4 virus-like particles (VLPs) in cohort A, with dose escalation, assessed before (day 0) and 4 weeks after the first dose (day 28) and 4 weeks after the second dose (day 56). Data in parentheses show the number of subjects per group. Abbreviation: ELISA, enzyme-linked immunosorbent assay.
