Table 1.
Demographic Characteristics, Secretor Status, and Blood Typing of Subjects Who Received 2 Doses of Either Equal Amounts of Norovirus GI.1 Virus-Like Particle (VLP) and a Consensus Norovirus GII.4 VLP or Placebo
| Variable | Cohort A Dose Group |
50/50-µg Dose Cohort |
||||||
|---|---|---|---|---|---|---|---|---|
| 5 µg | 15 µg | 50 µg | 150 µg | D | B | C | Placebo | |
| Target age range, y | 18–49 | 18–49 | 18–49 | 18–49 | 18–49 | 50–64 | 65–85 | 18–85 |
| Subjects, no. | 10 | 10 | 10 | 9 | 8 | 9 | 10 | 36 |
| Demographic characteristic | ||||||||
| Age, y, mean (range) | 33.2 (23–46) | 31.9 (19–46) | 31.9 (22–42) | 32.8 (23–49) | 32 (20–48) | 55.2 (51–59) | 68.5 (65–83) | 48.1 (19–73) |
| Male sex | 3 (30) | 4(40) | 3 (30) | 2 (22) | 5 (63) | 4 (44) | 2 (20) | 11 (31) |
| Ethnicity | ||||||||
| American Indian | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 (3) |
| Asian | 0 | 0 | 2 (20) | 2 (22) | 0 | 0 | 0 | 0 |
| Black | 2 (20) | 2 (20) | 2 (20) | 1 (11) | 5 (63) | 0 | 0 | 7 (19) |
| White | 8 (80) | 7 (70) | 6 (60) | 6 (67) | 3 (38) | 9 (100) | 10 (100) | 27 (75) |
| Multiracial | 0 | 1 (10) | 0 | 0 | 0 | 0 | 0 | 1 (3) |
| Norovirus secretor | 7 (70) | 8 (80) | 6 (60) | 9 (100) | 7 (88) | 6 (67) | 8 (80) | 28 (78) |
| Blood group | ||||||||
| A | 3 (30) | 3 (30) | 5 (50) | 3 (33) | 1 (13) | 2 (22) | 3 (30) | 12 (33) |
| B | 0 | 1 (10) | 0 | 1 (11) | 2 (25) | 2 (22) | 0 | 5 (14) |
| O | 6 (60) | 4 (40) | 5 (50) | 5 (56) | 5 (63) | 5 (56) | 7 (70) | 16 (44) |
| AB | 1 (10) | 2 (20) | 0 | 0 | 0 | 0 | 0 | 3 (8) |
Data are no. (%) of subjects, unless otherwise indicated.