Table 9.
Five-Year Total, Annual Average Totala, and Average Annual Age-Adjusted Incidence Ratesb for Brain and Other Central Nervous System Tumor by Sitec and Sex, CBTRUS Statistical Report: NPCR and SEER, 2009-2013
| Total | Male | Female | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ICD-O-3 Code | Site | 5-year total | Annual average | Rate | 95% CI | 5-year total | Annual average | Rate | 95% CI | 5-year total | Annual average | Rate | 95% CI |
| C71.0 | Cerebrum | 6,453 | 1,291 | 0.40 | (0.39-0.41) | 3,397 | 679 | 0.44 | (0.42-0.45) | 3,056 | 611 | 0.36 | (0.35-0.38) |
| C71.1-C71.4 | Frontal, temporal, parietal, and occipital lobes of the brain | 71,451 | 14,290 | 4.31 | (4.28-4.34) | 39,610 | 7,922 | 5.09 | (5.04-5.14) | 31,841 | 6,368 | 3.63 | (3.59-3.68) |
| C71.1 - Frontal lobe | 30,848 | 6,170 | 1.88 | (1.86-1.90) | 16,338 | 3,268 | 2.11 | (2.07-2.14) | 14,510 | 2,902 | 1.67 | (1.65-1.70) | |
| C71.2 - Temporal lobe | 22,974 | 4,595 | 1.38 | (1.36-1.40) | 13,600 | 2,720 | 1.74 | (1.71-1.77) | 9,374 | 1,875 | 1.07 | (1.05-1.09) | |
| C71.3 - Parietal lobe | 13,803 | 2,761 | 0.82 | (0.81-0.84) | 7,543 | 1,509 | 0.97 | (0.94-0.99) | 6,260 | 1,252 | 0.70 | (0.68-0.72) | |
| C71.4 - Occipital lobe | 3,826 | 765 | 0.23 | (0.22-0.24) | 2,129 | 426 | 0.27 | (0.26-0.29) | 1,697 | 339 | 0.19 | (0.18-0.20) | |
| C71.5 | Ventricle | 4,027 | 805 | 0.26 | (0.25-0.27) | 2,215 | 443 | 0.29 | (0.28-0.30) | 1,812 | 362 | 0.23 | (0.22-0.24) |
| C71.6 | Cerebellum | 9,075 | 1,815 | 0.59 | (0.58-0.60) | 4,874 | 975 | 0.65 | (0.63-0.67) | 4,201 | 840 | 0.54 | (0.52-0.56) |
| C71.7 | Brain stem | 5,572 | 1,114 | 0.37 | (0.36-0.38 | 3,003 | 601 | 0.40 | (0.38-0.41) | 2,569 | 514 | 0.34 | (0.32-0.35) |
| C71.8-C71.9 | Other brain | 32,956 | 6,591 | 1.99 | (1.97-2.01) | 17,209 | 3,442 | 2.25 | (2.21-2.28) | 15,747 | 3,149 | 1.77 | (1.74-1.80) |
| C72.0-C72.1 | Spinal cord and cauda equina | 11,104 | 2,221 | 0.69 | (0.68-0.70) | 5,697 | 1,139 | 0.73 | (0.71-0.75) | 5,407 | 1,081 | 0.65 | (0.63-0.67) |
| C72.2-C72.5 | Cranial nerves | 25,421 | 5,084 | 1.53 | (1.51-1.55) | 11,930 | 2,386 | 1.49 | (1.47-1.52) | 13,491 | 2,698 | 1.56 | (1.54-1.59) |
| C72.8-C72.9 | Other nervous system | 2,292 | 458 | 0.14 | (0.14-0.15) | 1,180 | 236 | 0.15 | (0.14-0.16) | 1,112 | 222 | 0.13 | (0.12-0.14) |
| C70.0-C70.9 | Meninges (cerebral & spinal) | 134,786 | 26,957 | 8.03 | (7.98-8.07) | 36,172 | 7,234 | 4.82 | (4.77-4.87) | 98,614 | 19,723 | 10.83 | (10.76-10.90) |
| C75.1-C75.2 | Pituitary and craniopharyngeal duct | 62,696 | 12,539 | 3.92 | (3.89-3.95) | 28,237 | 5,647 | 3.63 | (3.58-3.67) | 34,459 | 6,892 | 4.29 | (4.24-4.33) |
| C75.3 | Pineal | 1,614 | 323 | 0.11 | (0.10-0.11) | 899 | 180 | 0.12 | (0.11-0.13) | 715 | 143 | 0.09 | (0.08-0.10) |
| C30.0d | Olfactory tumors of the nasal cavity | 670 | 134 | 0.04 | (0.04-0.04) | 393 | 79 | 0.05 | (0.04-0.05) | 277 | 55 | 0.03 | (0.03-0.04) |
| TOTAL | 368,117 | 73,623 | 22.36 | (22.29-22.44) | 154,816 | 30,963 | 20.10 | (20.00-20.20) | 213,301 | 42,660 | 24.46 | (24.36-24.57) | |
aAnnual average cases are calculated by dividing the five-year total by five.
bRates are per 100,000 and are age adjusted to the 2000 US standard population.
cThe sites referred to in this table are loosely based on the categories and site codes defined in the SEER site/histology validation list.
dICD-O-3 histology codes 9522-9523 only.
Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology and End Results program; CI, confidence interval.