Table 4.

Bivariate analysis of biomarkers by time point for prediction of death or significant neurodevelopmental delay

Time Point	Biomarker	OR	Cutoff value*	AUC	P value	Accuracy (%)	Sensitivity (%)	Specificity (%)	Sample Size (n)	Event (n)
T72	IL10	1.89	0.850	0.67	0.021	76.60	63	86	47	19
	Tau	3.07	7.284	0.82	0.009	86.67	70	95	30	10
T96	IL10	1.76	0.560	0.72	0.039	79.07	67	86	43	15
	Tau	2.13	6.710	0.77	0.034	77.42	89	73	31	9
	GFAP	0.64	−2.767	0.72	0.032	70.00	31	96	40	16
	NRGN	0.65	−4.140	0.71	0.039	72.50	38	96	40	16
Late Average	IL10	1.74	0.660	0.68	0.026	75.47	67	81	53	21
	Tau	2.51	7.007	0.80	0.004	79.55	80	79	44	15
Minimum	Tau	1.94	7.284	0.70	0.044	72.97	31	96	37	13
Maximum	Tau	1.79	7.514	0.71	0.042	72.97	69	75	37	13

^*Cutoff value selected based on highest accuracy (correct classification)