Table 6.
Comparison of Study Outcomes by Most Disturbing Symptoms
| Rating Scale | Cognitive (n = 179) | Motor (n = 90) | Behavior (n = 105) | Language (n = 48) | Personality (n = 33) | Mood (n = 38) | Sleep (n = 18) | p-value (Omnibus F Test) |
|---|---|---|---|---|---|---|---|---|
| Caregiver QoL | 36.5 (8.0) | 36.1 (6.6) | 35.0 (7.6) | 36.6 (7.1) | 31.5 (8.2)** | 36.1 (6.0) | 31.1 (8.4) | 0.002 a |
| Care Recipient QoL | 27.1 (6.2) | 26.3 (5.0) | 25.9 (5.6) | 27.3 (5.9) | 24.1 (5.4) | 25.7 (5.0) | 24.2 (6.4) | 0.05 |
| Social Support | 59.9 (18.4) | 62.8 (17.9) | 60.4 (19.5) | 63.2 (20.6) | 53.9 (23.3) | 66.0 (16.6) | 49.4 (20.9) | 0.02 |
| PHQ-2 | 2.1 (1.8) | 2.0 (1.6) | 2.1 (1.8) | 1.7 (1.4) | 2.6 (1.7) | 1.8 (1.4) | 1.8 (1.7) | 0.27 |
| Perceived Change Index | 34.7 (6.8) | 34.5 (5.9) | 31.8 (8.0) | 36.4 (6.2) | 31.3 (8.9) | 32.7 (5.8) | 34.5 (6.7) | 0.001 b |
| Psychological Well-Being | 83.8 (12.7) | 82.1 (11.2) | 82.6 (12.8) | 84.5 (11.7) | 74.9 (14.6) | 86.7 (12.2) | 78.0 (12.0) | 0.002 c |
| Mastery | 30.9 (3.9) | 30.5 (4.0) | 30.7 (4.5) | 31.7 (3.5) | 29.7 (4.50 | 31.8 (4.2) | 30.6 (3.8) | 0.26 |
| Care Confidence | 12.3 (1.9) | 12.6 (1.7) | 12.1 (2.2) | 12.6 (1.6) | 11.7 (2.9) | 12.6 (2.0) | 11.4 (2.2) | 0.13 |
| Grief | 61.2 (13.4) | 59.0 (11.9) | 62.8 (13.5) | 61.0 (12.3) | 65.3 (13.7) | 57.9 (10.1) | 64.6 (13.2) | 0.08 |
| Burden | 24.8 (8.7) | 24.5 (7.5) | 26.9 (8.5) | 24.4 (8.1) | 29.4 (7.7) | 25.7 (7.1) | 25.1 (9.9) | 0.03 |
Mean (SD) Bold p-values are significant after correction for multiple comparisons (corrected p-value < 0.005) Notes on Post-hoc analyses:
a
Personality and Sleep symptoms are different from other disturbing symptoms, but not different from each other.
b
Behavior is different from cognitive, motor, and language; Personality is different from cognitive, motor, and language.
c
Personality is different from other symptoms except sleep, Sleep is different from mood. QoL, Quality of Life; PHQ-2, Patient Health Questionnaire.