Table 2.

Mean^a Relative UGT Expression in Human Tissue Specimens.^b

		NNAL-O-Gluc				NNAL-N-Gluc
		UGT1A9	UGT1A10	UGT2B7	UGT2B17	UGT1A4	UGT2B10
esophagus	mean	1.16 × 10−02	1.87 × 10−02	4.81 × 10−03	2.91 × 10−03	7.64 × 10−03	9.00 × 10−03
	SE	6.45 × 10−03	8.75 × 10−03	1.52 × 10−03	1.58 × 10−03	2.75 × 10−03	5.53 × 10−03
	% total	30.5%	49.2%	12.7%	7.7%	45.9%	54.1%
	# BLQ	0 of 12	0 of 12	3 of 12	2 of 12	0 of 12	0 of 12
floor of mouth	mean	9.18 × 10−03	1.16 × 10−02	3.06 × 10−03	1.43 × 10−03	1.10 × 10−02	4.67 × 10−03
	SE	3.63 × 10−03	3.35 × 10−03	1.78 × 10−03	7.57 × 10−04	3.41 × 10−03	2.20 × 10−03
	% total	36.3%	46.0%	12.1%	5.7%	70.3%	29.7%
	# BLQ	0 of 4	0 of 4	2 of 4	1 of 4	0 of 4	0 of 4
larynx	mean	2.12 × 10−02	5.26 × 10−02	1.65 × 10−02	1.62 × 10−02	1.51 × 10−02	1.18 × 10−02
	SE	1.07 × 10−02	1.74 × 10−02	1.25 × 10−02	1.36 × 10−02	5.72 × 10−03	8.66 × 10−03
	% total	19.9%	49.4%	15.5%	15.2%	56.3%	43.7%
	# BLQ	0 of 8	0 of 8	2 of 8	2 of 8	0 of 8	0 of 8
tongue	mean	1.68 × 10−02	2.18 × 10−02	1.24 × 10−02	5.02 × 10−03	1.86 × 10−02	1.15 × 10−02
	SE	1.14 × 10−02	1.48 × 10−02	7.46 × 10−03	3.04 × 10−03	1.35 × 10−02	7.01 × 10−03
	% total	30.0%	38.9%	22.1%	9.0%	61.7%	38.3%
	# BLQ	0 of 6	1 of 6	1 of 6	0 of 6	1 of 6	1 of 6
tonsil	mean	4.35 × 10−03	5.40 × 10−03	3.47 × 10−03	1.68 × 10−03	4.30 × 10−03	3.19 × 10−03
	SE	1.12 × 10−03	1.29 × 10−03	9.61 × 10−04	6.90 × 10−04	9.48 × 10−04	7.83 × 10−04
	% total	29.2%	36.2%	23.3%	11.3%	57.4%	42.6%
	# BLQ	0 of 6	0 of 6	1 of 6	1 of 6	0 of 6	0 of 6

^aMean relative expression (arbitrary units) was calculated to include UGTs with no expression.

^bThe % total for the expression of each UGT was calculated separately for NNAL-O-Gluc and NNAL-N-Gluc enzymes. BLQ, below limit of quantification (mean Ct > 35 cycles).