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Weighted PCA comparisons of baseline and endpoint fecal samples. Grouping by time and diet in (A) paper and (B) corncob bedding. Grouping by time and bedding in (C) ND and (D) HFD mice. Used 2-way PermANOVA. *P < 0.05, +P < 0.005, and ‡P < 0.001.
