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Structural features of the C. difficile toxin cysteine protease domain. (A) TcdA cysteine protease domain (PDB 3HO6) and (B) TcdB cysteine protease domain (PDB 3PEE) bound to InsP6 (268). The β-flap is colored purple, residues of the catalytic triad are depicted as blue sticks, and InsP6 is colored green.
