TABLE 7.
Sequence identity and similarity of LCT cysteine protease domains
| LCT | % sequence identity (% similarity)a |
||||
|---|---|---|---|---|---|
| TcdA | TcdB | TcsH | TcsL | TcnA | |
| TcdB | 57 (77) | ||||
| TcsH | 86 (95) | 58 (77) | |||
| TcsL | 57 (77) | 79 (90) | 59 (79) | ||
| TcnA | 33 (57) | 35 (57) | 36 (59) | 36 (60) | |
| TpeL | 53 (71) | 51 (70) | 54 (72) | 51 (72) | 38 (60) |
aSequence identity and similarity were calculated using Water (EMBOSS) local alignment. LCTs are from the following strains: C. difficile VPI 10463, P. sordellii VPI 9048, C. novyi 19402, and C. perfringens JGS1495. Under new subtyping analysis, TcdA and TcdB from C. difficile VPI 10463 are referred to as TcdA1 and TcdB1 (138).