FIG 3.

Schematic representation of MAT loci present in the subphylum Taphrinomycotina. MAT genes are shown in violet, other relevant genes in yellow, and the centromere-homologous sequence cenH in blue. The chromosomes carrying the genes are shown as black lines. The drawings are roughly to scale. The primary homothallic species Pneumocystis and Taphrina deformans each harbor a single MAT locus that includes three genes. The secondary homothallic species S. pombe harbors three MAT loci (or cassettes), each including two genes. The two MAT loci flanking cenH are silenced, whereas the third locus is active (here, for example, the M mating type). The cis-acting sequence motifs H1, H2, and H3, involved in mating-type switching and flanking each MAT locus, are shown in dark gray. The MAT locus is located on supercontigs (scaffolds) 9, 13, and 13, respectively, of the P. jirovecii, P. carinii, and P. murina genome assemblies (25). (Each scaffold presumably corresponds to one chromosome.)