TABLE 5.
Training set
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Training sets | FLAIR | ADC + FLAIR | Clin | Clin + Con MRI | All (combined model) |
ADC | 0.458 | 0.190 | 0.795 | 0.877 | <0.001* |
FLAIR | – | 0.041* | 0.477 | 0.523 | <0.001* |
ADC + FLAIR | – | – | 0.732 | 0.621 | 0.001* |
Clin | – | – | – | 0.555 | 0.003* |
Clin + Con MRI | – | – | – | – | 0.001* |
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Validation Set
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Validation sets | FLAIR | ADC + FLAIR | Clin | Clin + Con MRI | All (combined model) |
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ADC | 0.210 | 0.609 | 0.693 | 0.586 | 0.221 |
FLAIR | – | 0.036* | 0.532 | 0.616 | 0.011* |
ADC + FLAIR | – | – | 0.471 | 0.393 | 0.446 |
Clin | – | – | – | 0.323 | 0.031* |
Clin + Con MRI | – | – | – | – | 0.021* |
All indicates all factors, including clinical and conventional MRI factors and radiomics features. AUC, area under the curves; ADC, apparent diffusion coefficient; Clin, clinical variables; Con MRI, conventional MRI factors; FLAIR, fluid-attenuated inversion recovery. *P < 0.05.