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. 2021 Sep 16;12:726529. doi: 10.3389/fphar.2021.726529

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Copyright © 2021 Lu, Bi, Zhu, Huipeng, Duan and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Different expression gene (DEG) analysis of the integrated dataset. (A) Volcano plot of the 287 DEGs between normal and RA patients. Up: upregulated; Down: downregulated; Not: no change. (B) Unsupervised clustering heatmap of the DEGs between normal and RA patients, top 40 were shown. (C) MF enrichment of GO analysis for DEGs between normal and RA patients. MF: molecular function. (D) Volcano plot of the 1,564 DEGs between RA and OA patients. (E) Unsupervised clustering heatmap of the DEGs between RA and OA patients, top 40 were shown. (F) MF enrichment of GO analysis for DEGs between RA and OA patients.