Table 2.
Univariate analysis for locoregional recurrence.
| Variable | Test | Hazard ratio (95% CI) | P-value |
|---|---|---|---|
| Sex | Female vs. male | 0.928 (0.514, 1.675) | 0.8039 |
| Age | +1 year | 1.010 (0.987, 1.033) | 0.3938 |
| Smoking | Global test | 0.3281 | |
| Current smoker vs. stopped >6 m | 1.462 (0.843, 2.536) | 0.1764 | |
| Current smoker vs. never | 1.370 (0.655, 2.863) | 0.4029 | |
| Stopped >6 m vs. never | 0.937 (0.401, 2.189) | 0.8805 | |
| Ethyl | Global test | 0.0064 | |
| Stopped vs. yes | 2.215 (1.290, 3.801) | 0.0039 | |
| Stopped vs. none | 1.997 (1.195, 3.340) | 0.0083 | |
| Yes vs. none | 0.902 (0.537, 1.513) | 0.6956 | |
| Grade | +1 level | 0.574 (0.369, 0.892) | 0.0136 |
| Highest TNM stagea | +1 level | 1.935 (1.343, 2.788) | 0.0004 |
| Oral | Yes vs. no | 1.888 (0.764, 4.664) | 0.1683 |
| Oropharynx | Yes vs. no | 0.734 (0.475, 1.133) | 0.1621 |
| Glottis | Yes vs. no | 0.939 (0.485, 1.817) | 0.8513 |
| Hypopharynx | Yes vs. no | 1.435 (0.889, 2.316) | 0.1396 |
| Supraglottis | Yes vs. no | 1.428 (0.885, 2.305) | 0.1442 |
Continuous variables: HR > (<) 1 means higher (lower) risk for increasing level. Categorical variables: pairwise tests only presented if significant global P-value. Binary variables/pairwise tests: R > (<) 1 means higher (lower) risk for first category.
CI, confidence interval; m, months; TNM, tumor, node, metastasis stage.
a
In case patients had multiple tumors, the tumor with the highest TNM stage was used.