Table 6.

Bonding interactions displayed by neoxanthin against Acetylcholinesterase (AChE) and Butyrylcholinesterase (BChE)

Bonding interactins	AChE amino acid residues with positions	BChE amino acid residues with positions
Favoured water bridge interaction with nitrogen atom	Tyr_72, Asp_74, Thr_75, Gly_82, Trp_86, Tyr_124, His_284, Glu_285, Glu_292, and His_447	Asn_68, Ile_69, Asp_70, Gln_71, Ser_72, Gly_78, Ser_79, Trp_82, Leu_274, Ala_277, Ala_328, Phe_329, and Tyr_332
Hydrogen bonding interaction	Tyr_72, Asp_74, Asn_87, Tyr_124, Tyr_337, and Tyr_341	Asn_68, Asp_70, Gln_71, Ser_72, Gly_78, Ser_79, Trp_82, Ala_328, and Tyr_332
Hydrophobic interaction	Tyr_72, Leu_76, Trp_86, Trp_286, Leu_289, Val_294, Phe_297, Tyr_337, Phe_338, and Tyr_341	Met_81, Trp_82, Ala_277, Phe_278, Val_280, Tyr_282, Pro_285, Phe_329, Tyr_332, Trp_430, and Met_437
Ionic Interaction	–	Asn_68 and Ile_69