Table 3.

Associated genes in KEGG pathway and degree top 30 gene.

Ribosome biogenesis in eukaryotes	Degree top 30 genes
EMG1, GNL3, IMP3, MPHOSPH10, RIOK2, RPP38, UTP15, WDR3, WDR43, WDR75	TBP, PPARG, EXO1, CASP3, EMG1, CENPA, TNF, CCNF, CDC6, CREB1, TFB2M, UTP15, KIF11, CDCA8, KAT2B, RRS1, CHD1, MYC, IMP3, CUL1, WDR3, SIRT1, AURKA, BYSL, CXCL8, CREBBP, POLR1B, EGR1, STAT3, NDC80

AURKA = aurora kinase A, BYSL = bystin like, EMG1 = essential for mitotic growth 1, CASP3 = caspase 3, CCNF = cyclin F, CDCA8 = cell division cycle associated 8, CDC6 = cell division cycle 6, CHD1 = chromodomain helicase DNA binding protein 1, CREB1 = CAMP responsive element binding protein 1, CREBBP = CREB binding protein, CENPA = centromere protein A, CXCL8 = C-X-C motif chemokine ligand 8, CUL1 = cullin 1, EGR1 = early growth response 1, EXO1 = exonuclease 1, GNL3 = G protein nucleolar 3, IMP3 = U3 SnoRNP protein 3 homolog, KAT2B = lysine acetyltransferase 2B, KEGG = kyoto encyclopedia of genes and genomes, KIF11 = kinesin family member 11, MYC = MYC proto-oncogene, BHLH transcription factor, NDC80 = NDC80 kinetochore complex component, PPARG = peroxisome proliferator activated receptor gamma, POLR1B = RNA polymerase I subunit B, RPP38 = ribonuclease P/MRP subunit P38, RRS1 = ribosome biogenesis regulator 1 homolog, RIOK2 = RIO kinase 2, STAT3 = signal transducer and activator of transcription 3, SIRT1 = sirtuin 1, TNF = tumor necrosis factor, TFB2M = transcription factor B2, mitochondrial, UTP15 = U3 small nucleolar RNA-associated protein 15 homolog, WDR43 = WD repeat domain 43, WDR75 = WD repeat domain 75, WDR3 = WD repeat domain 3.