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. 2021 Sep 23;2021:5544571. doi: 10.1155/2021/5544571

Table 5.

Relationship between patterns and other outcome measures.

Clusters Corresponding TTH subtypes MIDAS Outcome measures Comorbidity (%)
PSS (mean ± SD) Physical Mental
Intensity (0–10) Disability level By PSS items (scores of item 3: the higher, the worse) (reversed scoring of item 5 and 8: the lower, the better) By “perceived coping” factor (combined items of 4, 5, 7, and 8; the lower, the better in coping)
Cluster 1: ascendant hyperactivity of liver yang (n = 46) graphic file with name ECAM2021-5544571.tab5.i001.jpg Moderate pain (5.5) Moderate disability (grade III; 9 days) Item 3: (2.46 ± 0.925) most often (5.04 ± 3.025) 43.40% 17.40%
In the last month, how often have you felt nervous and “stressed”?' Best performance in perceived coping among clusters.
Item 5: (1.39±0.755) most often Cluster being different from clusters 3 and 4
‘In the last month, how often have you felt that things were going your way?'

Cluster 2: dual Qi and blood deficiency (n = 34) graphic file with name ECAM2021-5544571.tab5.i002.jpg Moderate pain (6.3) Severe disability (grade IV; 31 days) Item 8: (1.44±0.982) most often (5.18 ± 3.070) 55.90% 26.50%
‘In the last month, how often have you felt that you were on top of things?' Cluster being different from clusters 3 and 4

Cluster 3: liver depression forming fire (n = 46) graphic file with name ECAM2021-5544571.tab5.i003.jpg Moderate pain (5.4) Severe disability (grade IV; 24 days) Item 5: (2.14±1.104) least often (7.35 ± 4.018) 41.30% 10.90%
‘In the last month, how often have you felt that things were going your way?' Cluster being different from clusters 1 and 2
Item 8: (2.26±1.049) LEASTLY often
‘In the last month, how often have you felt that you were on top of things?'

Cluster 4: unlabelled group (n = 44) graphic file with name ECAM2021-5544571.tab5.i004.jpg Mild pain (4.7) Moderate disability (grade III; 19 days) Item 3: (1.39±0.868) LEASTLY often (7.59 ± 3.329) 34.10% 0.00%
In the last month, how often have you felt nervous and “stressed”? Poorest performance in perceived coping.
Cluster being different from clusters 1 and 2

Note 1: in this table, “iETTH” stands for “infrequent ETTH,” whereas the “fETTH” is the abbreviation of “frequent ETTH.” Note 2: “”: the mean difference of PSS is significant among clusters at the 0.17 (0.05/3) level.