Table 2.
Allelic and genotypic frequency of maternal RNLS rs10887800 and rs2576178 polymorphisms in IS patients and control group.
| IS (N = 154) | Control (N = 165) | P value | OR (95% CI) | ||
|---|---|---|---|---|---|
| RNLS rs10887800 | |||||
| Codominant | |||||
| AA, n (%) | 41 (26.6) | 57 (34.5) | 1 | ||
| AG, n (%) | 88 (57.1) | 75 (45.5) | 0.054 | 1.7 (1-2.7) | 0.058 |
| GG, n (%) | 25 (33) | 33 (20) | 0.894 | 1.1 (0.5-2) | 0.878 |
| Dominant (AG + GG vs. AA) | 0.122 | 1.5 (0.9-2.4) | 0.126 | ||
| Recessive (GG vs. AG + AA) | 0.363 | 0.8 (0.4-1.4) | 0.385 | ||
| Overdominant (AG vs. AA+ GG) | 0.033 | 1.6 (1-2.5) | 0.037 | ||
| Allele | |||||
| A, n (%) | 170 (55) | 189 (57) | 1 | ||
| G, n (%) | 138 (45) | 141 (43) | 0.632 | 1.1 (0.8-1.5) | |
| RNLS rs2576178 | |||||
| AA, n (%) | 115 (74.7) | 115 (69.7) | 1 | ||
| AG, n (%) | 32 (20.8) | 42 (25.5) | 0.306 | 0.8 (0.5-1.3) | 0.313 |
| GG, n (%) | 7 (4.5) | 8 (4.8) | 0.756 | 0.9 (0.3-2.4) | 0.803 |
| Dominant model (AG + GG vs. AA) | 0.307 | 0.8 (0.5-1.3) | 0.323 | ||
| Recessive model (GG vs. AG + AA) | 0.855 | 0.9 (0.3-2.6) | 0.899 | ||
| Overdominant (AG vs. AA+GG) | 0.321 | 0.8 (0.5-1.3) | 0.324 | ||
| Allele | |||||
| A, n (%) | 262 (85) | 272 (82) | 1 | ||
| G, n (%) | 46 (15) | 58 (18) | 0.392 | 0.8 (0.5-1.3) |