Table 1.
Comparison of urachal vs. nonurachal bladder adenocarcinoma presentation.
| Urachal [3] | Non-urachal [3, 5] | |
|---|---|---|
| Origin of disease | Urachal remnant | Bladder urothelium |
| Age | 5-6th decade of life | 6-7th decade of life |
| Location of disease | Bladder dome, anterior wall | Trigone, posterior wall, but can arise throughout |
| Immunohistochemical staining | CK20, CDX2 (+/- CK7, B-catenin, HM cytokeratin) | Variable based on histological phenotype |
| Possible symptoms | Umbilical discharge/bleeding, hematuria, lower urinary tract symptoms | Hematuria, lower urinary tract symptoms |