TABLE 3.
Group | Studies (n) | ES (95% CI) | P value | P-within subgroups heterogeneity | P-between subgroups heterogeneity | tau2 |
---|---|---|---|---|---|---|
Total cancer | ||||||
total | 18 | 1.04 (0.96, 1.11) | 0.345 | 0.178 | — | 0.005 |
Gender | ||||||
Female | 7 | 1.05 (0.94, 1.18) | 0.311 | 0.113 | 0.706 | 0.017 |
Male | 6 | 1.02 (0.95, 1.10) | 0.474 | 0.318 | 0.001 | |
Both | 5 | 1.09 (0.94, 1.27) | 0.217 | 0.258 | 0.010 | |
BMI adjustment | ||||||
Yes | 11 | 0.99 (0.87, 1.11) | 0.881 | 0.333 | 0.327 | 0.002 |
No | 7 | 1.06 (0.99, 1.13) | 0.069 | 0.129 | 0.021 | |
Continent | ||||||
America | 9 | 1.01 (0.93, 1.10) | 0.678 | 0.394 | 0.111 | 0.001 |
Europe | 8 | 1.08 (1.004, 1.18) | 0.039 | 0.298 | 0.005 | |
Australia | 1 | 0.70 (0.44, 1.10) | 0.127 | — | 0.127 | |
Number of cases | ||||||
<500 | 11 | 0.99 (0.87, 1.11) | 0.881 | 0.333 | 0.327 | 0.005 |
≥500 | 7 | 1.06 (0.99, 1.13) | 0.069 | 0.129 | 0.005 | |
Colorectal cancer | ||||||
Study design | ||||||
Cohort | 5 | 1.09 (0.91, 1.31) | 0.310 | 0.132 | 0.99 | 0.017 |
Case-control | 4 | 1.13 (0.86, 1.49) | 0.372 | 0.152 | 0.033 | |
Gender | ||||||
Female | 4 | 1.08 (0.83, 1.40) | 0.133 | 0.07 | 0.97 | 0.037 |
Both | 5 | 1.12 (0.93, 1.35) | 0.102 | 0.259 | 0.010 | |
Energy adjustment | ||||||
Yes | 8 | 1.08 (0.94, 1.26) | 0.255 | 0.130 | 0.28 | 0.015 |
No | 1 | 1.46 (0.90, 2.36) | 0.126 | — | <0.001 | |
BMI adjustment | ||||||
Yes | 6 | 1.03 (0.87, 1.22) | 0.703 | 0.187 | 0.04 | 0.014 |
No | 3 | 1.29 (1.09, 1.52) | 0.003 | 0.658 | <0.001 | |
Continent | ||||||
America | 4 | 0.89 (0.73, 1.09) | 0.269 | 0.386 | 0.04 | 0.0006 |
Europe | 3 | 1.24 (1.07, 1.44) | 0.003 | 0.575 | <0.001 | |
Australia | 1 | 1.14 (0.86, 1.49) | 0.346 | — | <0.001 | |
Africa | 1 | 1.46 (0.90, 2.36) | 0.126 | — | <0.001 | |
Number of cases | ||||||
<400 | 5 | 1.12 (0.87, 1.45) | 0.345 | 0.245 | 0.98 | 0.021 |
≥400 | 4 | 1.09 (0.91, 1.32) | 0.325 | 0.075 | 0.020 | |
Pancreatic cancer | ||||||
Study design | ||||||
Cohort | 2 | 1.23 (0.87, 1.72) | 0.228 | 0.296 | 0.83 | 0.005 |
Case-control | 3 | 1.23 (0.95, 1.60) | 0.110 | 0.147 | 0.025 | |
Gender | ||||||
Male | 1 | 1.02 (0.63, 1.64) | 0.935 | — | 0.49 | <0.001 |
Both | 4 | 1.26 (1.02, 1.55) | 0.032 | 0.214 | 0.015 | |
BMI adjustment | ||||||
Yes | 2 | 1.59 (1.15, 2.19) | 0.004 | 0.505 | 0.04 | <0.001 |
No | 3 | 1.09 (0.91, 1.30) | 0.315 | 0.791 | <0.001 | |
Number of cases | ||||||
<300 | 2 | 1.05 (0.85, 1.30) | 0.640 | 0.888 | 0.08 | <0.001 |
≥300 | 3 | 1.38 (1.10, 1.73) | 0.005 | 0.378 | <0.001 | |
Continent | ||||||
America | 1 | 1.20 (0.87, 1.65) | 0.266 | — | 0.33 | <0.001 |
Europe | 3 | 1.38 (1.01, 1.89) | 0.040 | 0.253 | 0.020 | |
Asia | 1 | 1.06 (0.83, 1.34) | 0.630 | — | <0.001 | |
Breast cancer | ||||||
Study design | ||||||
Cohort | 2 | 0.95 (0.80, 1.14) | 0.646 | 0.253 | 0.98 | 23 |
Case-control | 2 | 0.95 (0.82, 1.10) | 0.543 | 0.089 | 65 | |
BMI adjustment | ||||||
Yes | 3 | 0.93 (0.83, 1.05) | 0.290 | 0.211 | 0.29 | 35.7 |
No | 1 | 1.14 (0.80, 1.61) | 0.459 | — | — | |
Energy adjustment | ||||||
Yes | 3 | 0.92 (0.82, 1.04) | 0.209 | 0.455 | 0.10 | 0 |
No | 1 | 1.23 (0.89, 1.69) | 0.202 | — | — | |
Number of cases | ||||||
<1000 | 2 | 1.18 (0.93, 1.50) | 0.155 | 0.75 | 0.04 | 0 |
≥1000 | 2 | 0.90 (0.79, 1.02) | 0.103 | 0.99 | 0 | |
Prostate cancer | ||||||
Study design | ||||||
Cohort | 4 | 1.03 (0.96, 1.12) | 0.318 | 0.405 | 0.28 | 0 |
Case-control | 1 | 0.90 (0.69, 1.15) | 0.414 | — | — | |
BMI adjustment | ||||||
Yes | 4 | 1.04 (0.97, 1.12) | 0.246 | 0.612 | 0.13 | 0 |
No | 1 | 0.87 (0.69, 1.09) | 0.233 | — | — | |
Dietary assessment tool | ||||||
FFQ | 4 | 1.02 (0.95, 1.10) | 0.436 | 0.274 | 0.67 | 22 |
24-h dietary records | 1 | 0.93 (0.57, 1.49) | 0.765 | — | — | |
Number of cases | ||||||
<1000 | 2 | 0.88 (0.71, 1.08) | 0.228 | 0.804 | 0.12 | 0 |
≥1000 | 3 | 1.04 (0.97, 1.13) | 0.221 | 0.456 | 0 | |
Continent | ||||||
America | 1 | 1.07 (0.96, 1.19) | 0.217 | — | 0.31 | — |
Europe | 4 | 0.99 (0.90, 1.09) | 0.890 | 0.386 | 1.3 |
ES, effect size.