Table 2.
Subgroup analysis of in-hospital mortality
| Analysis | N | R-OR (95% CI) | P | F-OR (95% CI) | P | I2 | Ph |
|---|---|---|---|---|---|---|---|
| In-hospital mortality | 20 | 2.07 (1.60, 2.67) | 0 | 1.10 (1.60, 2.67) | 0 | 91.3% | 0.000 |
| Subgroup 1: Single center | 7 | 2.15 (1.17, 2.67) | 0.014 | 2.15 (1.58, 2.92) | 0 | 70.2% | 0.003 |
| Multicenter | 13 | 2.01 (1.51, 2.68) | 0.000 | 1.09 (1.04, 1.13) | 0 | 93.3% | 0.000 |
| Subgroup 2: Sample size<200 | 4 | 3.50 (1.98, 6.17) | 0.003 | 3.50 (1.98, 6.17) | 0 | 0.1% | 0.391 |
| Sample size ≥ 200 | 16 | 1.95 (1.50, 2.54) | 0 | 1.10 (1.05, 1.14) | 0 | 92.4% | 0.000 |
| Subgroup 3: Univariate analysis | 13 | 2.49 (1.99, 3.12) | 0 | 2.19 (1.95, 2.46) | 0 | 46.9% | 0.032 |
| Multivariate analysis | 7 | 1.34 (1.01, 1.78) | 0.040 | 1.00 (0.96, 1.05) | 0.888 | 87.1% | 0.000 |
| Subgroup 4: NOS<6 | 8 | 2.47 (1.41, 4.33) | 0.002 | 1.02 (0.98, 1.07) | 0.353 | 93.1% | 0.000 |
| NOS ≥ 6 | 12 | 1.85 (1.37, 2.51) | 0 | 1.52 (1.38, 1.66) | 0 | 81.7% | 0.000 |
N: number of studies; R-OR: odds ratio calculated by random-effects model; F-OR: odds ratio calculated by fixed-effects model; 95% CI: 95% confidence interval; pH: P values of Q test for heterogeneity.