Table 1.
Ingredient components and pharmacological activities in Ninjin'yoeito(人参養栄湯).
| Ingredient name | Component Ratio(g) | Phamacological activities | References | |
|---|---|---|---|---|
| Ginseng | 人参 | 3.0 | immune enhancement, anti-inflammation effects, antioxidant effects, memory enhancement, platelet-aggregation inhibitory effects, improvement of menopausal disorders, and induction of metabolic energy |
(Han et al., 2018) (Kim et al., 2010) (Kim, 2012) (Kim et al., 2014) (Wang et al., 2013) (Yang et al., 2014) (MATSUDA et al., 1986) |
| Japanese angelica root | 当帰 | 4.0 | anti-inflammatory effects | (Uto et al., 2015) |
| Rehmannia root | 地黄 | 4.0 | hypoglycemic effect, diuretic effect promoting effect on erythrocyte deformability and fibrinolytic activity blood coagulation inhibiting effect |
(Kitagawa et al., 1971) (KUBO et al., 1994) (Matsuda, 1986) |
| Atractylodes rhizome | 白朮 | 4.0 | anti-inflammatory and antinociceptive effects | (Chen et al., 2016) |
| Poria sclerotium | 茯苓 | 4.0 | anti-inflammatory, anti-apoptotic, and anti-immunologic rejection effects. | (Lee et al., 2013) (Zhang et al., 2009) (Wang et al., 2015) |
| Peony Root | 芍薬 | 2.0 | anti-inflammatory and immunomodulatory effects blood coagulation inhibiting effect |
(He and Dai, 2011) (Sakuragawa, 1983) |
| Citrus unshiu peel | 陳皮 | 2.0 | antioxidant, anti-inflammatory, antibacterial properties, and anti-cancer activity antiobesity and lipid-improving effect |
(Im Ahn et al., 2017) (Kang et al., 2018) |
| Polygala root | 遠志 | 2.0 | anti-dementia, anti-aging, anti-inflammatory, and anti-oxidant |
(Yuan et al., 2012) (Zhang et al., 2008) (Lee et al., 2009) (Shin et al., 2009) |
| Astragalus root | 黄耆 | 1.5 | increase telomerase activity, anti-oxidant, anti-inflammatory, immune-regulatory, anticancer, hypolipidemic, antihyperglycemic, hepatoprotective, expectorant, and diuretic effects | (Liu et al., 2017) (Jiangwei et al., 2011) (Ryu et al., 2008) (Chan et al., 2009) (Nalbantsoy et al., 2012) |
| Cinnamon bark | 桂皮 | 2.5 | antidiabetic effects anti-thrombic activities |
(Crawford and Crawford, 2018) (Olefsky, 2000) (MATSUDA et al., 1987) |
| Schisandra fruit | 五味子 | 1.0 | anti-hyperlipidemia effect, antiaging effect improving learning and memory impairment antitussive activity |
(Sun et al., 2018) (Zhong et al., 2016) |
| Glycyrrhiza | 甘草 | 1.0 | anti-inflammatory, anti-cancer and immunomodulatory effects | (Yin et al., 2018) (Menegazzi et al., 2008) (Wang et al., 2011) (Zeng et al., 2015) (Hong et al., 2009) |
7.5 g of Ninjin'yoeito extract granules contains 6700 mg of a dried extract of the following mixed crude drugs.