Table 2.
Univariable Models | Multivariable Model | |||||||
---|---|---|---|---|---|---|---|---|
Characteristic | HR1 | 95% CI1 | p-value | Characteristic | HR1 | 95% CI1 | p-value | |
SUVmax | 1.04 | 1.01, 1.07 | 0.01 | |||||
sumSUVmax | 1.02 | 1.01, 1.03 | <0.001 | sumSUV max (for 5 units) | 1.09 | 1.04, 1.14 | <0.001 | |
log-MTV | 1.16 | 0.96, 1.40 | 0.13 | |||||
log-sumMTV | 1.19 | 0.99, 1.44 | 0.06 | |||||
log-TLG | 1.1 | 0.97, 1.25 | 0.11 | |||||
log-sumTLG | 1.12 | 0.99, 1.26 | 0.07 | |||||
Age | 0.99 | 0.96, 1.01 | 0.35 | |||||
ECOG | 0.90 | |||||||
0 | Ref. | |||||||
1 | 1.13 | 0.51, 2.51 | ||||||
2 | 1.29 | 0.43, 3.89 | ||||||
Treatment | 0.01 | Treatment | 0.02 | |||||
Combination | Ref. | Combination | Ref. | |||||
Single agent | 3.09 | 1.18, 8.09 | Single agent | 2.73 | 1.03, 7.25 | |||
MYD88 | 0.76 | |||||||
Mutated | Ref. | |||||||
Wild type | 0.9 | 0.44, 1.84 | ||||||
CD79B | 0.73 | |||||||
Mutated | Ref. | |||||||
Wild type | 1.14 | 0.55, 2.35 | ||||||
N lesions | 0.08 | |||||||
0 | Ref. | |||||||
1 | 1.32 | 0.55, 3.15 | ||||||
2+ | 2.78 | 1.11, 7.00 | ||||||
log-Total tumor volume (cm3) | 1.16 | 0.99, 1.35 | 0.05 |
HR = Hazard Ratio, CI = Confidence Interval