Skip to main content
. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Clin Transplant. 2021 May 31;35(8):e14369. doi: 10.1111/ctr.14369

Figure 5:

Figure 5:

Proliferation after RATG is proportional to depletion. Frequency (%) of A) Ki-67+ CD4+ T cells, B) Ki-67+ CD8 T cells C) CD4+ RTEs (CD31+ Tnaive), and D) CD8+ RTEs (CD103+ Tnaive). E) Correlation of maximum depletion with maximum proliferation. F) Correlation of maximum proliferation with minium frequency RTE. G) Representative histology of thymus with staining using polyclonal anti-rabbit Ab (brown). All comparisons in panels A-D by Mixed effects model comparing for the main effects of treatment, time and interaction of treatment and time with Dunnett’s post-test for comparison of huATG vs. rhATG#5 or rhATG#6. ¶= p<0.05 for treatment, †=p<0.05 for time, and ‡=p<0.05 for interaction of treatment and time. *=p<0.05 for huATG vs. rhATG#5, ^=p<0.05 for huATG vs. rhATG#6. Panels E and F with simple linear regression. P-value and R2 reported. P<0.05 significant.