Table 1:
Clinical and laboratory parameters of diabetic vs. non-diabetic patients.
| Non-Diabetic | Diabetic | ||
|---|---|---|---|
| n=13 | n=13 | P value | |
| Age (years) | 65.4 ± 6 | 68.2 ± 6 | 0.24 |
| Male n (%) | 7 (46) | 12 (92) | 0.08 |
| Body mass index (kg/m2) | n.d. | 30.7 ± 4.9 | n.d. |
| Fasting glucose (mg/dL) | n.d. | 139 ± 39 | n.d. |
| HbA1c (%) | 5.6 ± 0.3 | 7.2 ± 0.9 | <0.001 |
| Oral anti-diabetics n (%) | 0 (0) | 13 (100) | <0.001 |
| Insulin treatment n (%) | 0 (0) | 13 (100) | <0.001 |
| Arterial hypertension n (%) | 2 (15) | 13 (100) | 0.157 |
| Anti-hypertensive medication n (%) | 3 (23) | 13 (100) | 0.08 |
| Reported diastolic dysfunction n (%) | 0 (0) | 13 (100) | <0.001 |
| 12(S)-HETE (ng/mL) | 17.6 ± 10 | 264.2 ± 336 | 0.014 |
Values are presented as mean±SD or n in % of total cohort. P-values were determined by Student’s t-test, except for Type 2 diabetes mellitus (DM), medication and hypertension (categorical variables). Bold P-values indicate significance, n.d. - not determined.