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. Author manuscript; available in PMC: 2022 Feb 26.
Published in final edited form as: Nat Neurosci. 2021 Aug 26;24(10):1367–1376. doi: 10.1038/s41593-021-00908-3

Extended Data Fig. 5. MAGMA gene-property analysis.

Extended Data Fig. 5

Bar plot of the −log10(P from one-sided Z-tests) of the point estimate from a generalized least squares regression. The analysis identified that the externalizing GWAS is significantly enriched in brain and pituitary gland tissues (Supplementary Information section 6). Dashed line denotes Bonferroni-corrected significance, adjusted for testing 54 tissues (one-sided P < 9.26×10−4). 14 tissues were significantly associated with the externalizing GWAS, including 13 brain related tissues and the pituitary tissue. The results are also report in Supplementary Table 15.