Table 4.
Results of positively scored children with cancer after routine clinical genetic evaluation and the (negatively scored) control group
| Patients with positive assessment (n = 208) | Patients with negative assessment (n = 155) | |||||
|---|---|---|---|---|---|---|
| Double positive (n = 116) | Single positive (n = 92) | Negative control group after randomization (n = 40) | ||||
| Patients seen for routine consultation CGa | 105 | 81 | 35 | |||
| TPS ruled out without further DNA diagnostics | 33 | (31%) | 56 | (69%) | 29 | (83%) |
| Further DNA diagnostics | ||||||
| Offered, but declined | 9 | (9%) | 4 | (5%) | 0 | |
| Negative | 57 | (54%) | 19 | (23%) | 6 | (17%) |
| Positive, TPS found | 4 | (4%) | 0 | 0 | ||
| Unclear significance | 2 | (2%) | 2 | (3%) | 0 | |
aSome patients refrained from further consultation or were unable to visit due to their illness