Table 2.
Correlations of levels and composition of the circulating microbiome with selected clinical parameters in hemodialysis patients
| Characteristic | Age | Vintage | LPS | CRPa | TNF-α | IL-6a | MCP-1 | Nrf2 |
|---|---|---|---|---|---|---|---|---|
| 16S rRNA | –0.18 | 0.014 | 0.11 | 0.27 | 0.30 | –0.20 | –0.33 | –0.078 |
| 16S Shannon Index | 0.093 | 0.081 | –0.017 | 0.40b | 0.016 | 0.094 | 0.12 | 0.22 |
| Actinobacteria | 0.26 | 0.13 | –0.039 | –0.13 | 0.20 | 0.095 | –0.086 | –0.41b |
| Proteobacteria | –0.30 | 0.17 | 0.26 | 0.28 | 0.0011 | 0.13 | 0.10 | 0.42b |
Data are presented as Spearman rank correlation (rho).
CRP, C-reactive protein; IL-6, interleukin-6; LPS, lipopolysaccharide; MCP-1, monocyte chemoattractant protein−1; Nrf2, nuclear factor erythroid 2−related factor 2; rRNA, ribosomal RNA; TNF-α, tumor necrosis factor−α.
Values were log transformed.
P <0.05.