Table 1.
Baseline demographic characteristics of the populations
| Variable | Matched cohorts |
FSGS nephrotic subpopulations |
||||
|---|---|---|---|---|---|---|
| FSGS (n = 844) | Non-FSGS controls (n = 1,688) | P value | Nephrotic range (n = 112) | Nonnephrotic (n = 196) | P-value | |
| Male | 484 (57.4) | 968 (57.4) | 1.00 | 60 (53.6) | 104 (53.1) | 0.9312 |
| Age, years | 54.7 ± 18.4 | 54.7 ± 18.4 | 1.00 | 57.0 ± 19.0 | 53.9 ± 17.4 | 0.1358 |
| Age group | 1.00 | 0.0537 | ||||
| <18 years | 22 (2.6) | 44 (2.6) | 3 (2.7) | 3 (1.5) | ||
| 18–65 years | 535 (63.4) | 1,070 (63.4) | 60 (53.6) | 133 (67.9) | ||
| >65 years | 287 (34.0) | 574 (34.0) | 49 (43.8) | 60 (30.6) | ||
| Race/ethnicity | 1.00 | 0.1280 | ||||
| Asian | 51 (6.0) | 102 (6.0) | 5 (4.5) | 14 (7.1) | ||
| Black | 174 (20.6) | 348 (20.6) | 14 (12.5) | 42 (21.4) | ||
| Hispanic | 139 (16.5) | 278 (16.5) | 29 (25.9) | 38 (19.4) | ||
| White | 480 (56.9) | 960 (56.9) | 64 (57.1) | 102 (52.0) | ||
| Geographic region | < 0.0001 | 0.6527 | ||||
| Northeast | 88 (10.4) | 138 (8.2) | 13 (11.6) | 22 (11.2) | ||
| Midwest | 188 (22.3) | 320 (19.0) | 17 (15.2) | 22 (11.2) | ||
| South | 405 (48.0) | 717 (42.5) | 60 (53.6) | 104 (53.1) | ||
| West | 158 (18.7) | 464 (27.5) | 22 (19.6) | 48 (24.5) | ||
| Unknown | 5 (0.6) | 49 (2.9) | ||||
| Household income | 0.0144 | 0.3265 | ||||
| <$40K | 206 (24.4) | 327 (19.4) | 18 (16.1) | 46 (23.5) | ||
| $40K–$49K | 69 (8.2) | 120 (7.1) | 9 (8.0) | 14 (7.1) | ||
| $50K–$59K | 66 (7.8) | 128 (7.6) | 12 (10.7) | 12 (6.1) | ||
| $60K–$74K | 75 (8.9) | 164 (9.7) | 13 (11.6) | 17 (8.7) | ||
| $75K–$99K | 113 (13.4) | 200 (11.9) | 22 (19.6) | 27 (13.8) | ||
| ≥$100K | 185 (21.9) | 446 (26.4) | 23 (20.5) | 48 (24.5) | ||
| Unknown | 130 (15.4) | 303 (18.0) | 15 (13.4) | 32 (16.3) | ||
| Insurance | 0.0102 | 0.0938 | ||||
| Commercial | 466 (55.2) | 1,022 (60.6) | 57 (50.9) | 119 (60.7) | ||
| Medicare | 378 (44.8) | 666 (39.5) | 55 (49.1) | 77 (39.3) | ||
FSGS, focal segmental glomerulosclerosis.
Continuous variables are expressed as mean ± SD, and categorical variables as n and (%).