Table 5.

Effect sizes (Cohen’s d), AUC values, and quantitative agreement with 0–60 DVR for 0–40 DVR and 20–40 SUVr with the aim to discriminate PSP from α-synucleinopathies

A) Cohen’s d	GPe	GPi	PUT	STN	SN	DMB	MPFC	DLPFC	DN
0–60	1.579	1.961	1.317	1.428	0.927	0.293	0.784	0.209	1.120
0–40	1.487	1.986	1.228	1.381	0.891	0.258	0.782	0.276	1.114
20–40	1.348	1.727	1.284	1.531	1.143	0.131	0.410	0.436	1.128
B) AUC	GPe	GPi	PUT	STN	SN	DMB	MPFC	DLPFC	DN
0–60	0.903	0.976	0.822	0.870	0.765	0.643	0.744	0.561	0.805
0–40	0.892	0.973	0.797	0.876	0.749	0.624	0.742	0.581	0.819
20–40	0.859	0.949	0.843	0.878	0.843	0.589	0.661	0.619	0.814
C) R/RMSE	GPe	GPi	PUT	STN	SN	DMB	MPFC	DLPFC	DN
0–40 DVR	0.976/2.2%	0.978/2.4%	0.994/1.7%	0.978/1.9%	0.983/1.0%	0.991/2.5%	0.994/1.2%	0.969/1.0%	0.991/0.7%
20–40 SUVr	0.893/11.9%	0.754/12.6%	0.898/4.7%	0.621/7.1%	0.736/11.7%	0.956/6.6%	0.958/3.9%	0.889/11.3%	0.925/4.6%

GPe globus pallidus externus, GPi globus pallidus internus, PUT putamen, STN subthalamic nucleus, SN substantia nigra, DMB dorsal midbrain, MPFC medial prefrontal cortex, DLPFC dorsolateral prefrontal cortex, DN dentate nucleus, DVR distribution volume ratio, SUVr standardized uptake value ratio, R Pearson’s correlation coefficient, RMSE root-mean-square-error, AUC area under the curve