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. 2021 May 3;48(12):3886–3902. doi: 10.1007/s00259-021-05362-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Modulation of quantitative [18F]FDG-PET/CT measures upon clinical remission in longitudinal studies. Per scan data or per patient data at baseline and during serial scans were obtained, if the disease activity during the scans was clearly defined in the studies. a Representative [18F]FDG-PET/CT scans of a patients with giant cell arteritis (GCA). Scans were performed at diagnosis and during immunosuppressive treatment. b Timing of follow-up scans and c quantitative PET measures (including no. of positive arteries, composite PET scores, target to background ratio (TBRs) in the included, longitudinal studies. CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; MTX, methotrexate; PRED, prednisolone; TCZ, tocilizumab (anti-IL-6 receptor therapy)