Table 1.
Study and patient characteristics
| Authors | Country | Study design | Type of LVV | Reference standard for LVV diagnosis | No. of [18F]FDG-PET/CT scans (no. of patients) | Median or * mean age (yrs) | % male | CRP/ESR available | |
|---|---|---|---|---|---|---|---|---|---|
| Alibaz-Oner et al. (2015) | Turkey | Prospective | Cross sectional | TAK | ACR criteria 1990 | 14 (14) | 39* | 21 | No |
| Banerjee et al. (2020) | USA | Prospective | Longitudinal | TAK, GCA | ACR criteria 1990 or modifiedcriteria for GCA | 156 (52; 21 TAK and 31 GCA) | 30 (TAK); 72 (GCA) | 24 (TAK); 26 (GCA) | Yes |
| Bruls et al. (2016) | Belgium | Prospective | Longitudinal | TAK, GCA, aortitis | Clinical, biochemical, biopsyand PET/CT results + ACRcriteria 1990 (n = 4) | 45 (15; 2 TAK, 4 GCA, 6 aortitis, 3 other) | 65* total population | 44 total population | No |
| Castellani et al. (2016) | Italy | Retrospective | Cross sectional and longitudinal | TAK, GCA | Not specified | 41 (21; 5 TAK and 16 GCA) | 61* TAK; 70* GCA | 33 total population; 33 (TAK); 22 (GCA) | Yes |
| de Boysson et al. (2017) | France | Retrospective | Longitudinal | GCA | ACR criteria 1990 or 2 ACRcriteria in combinationwith PET/CT positivity | 59 (25) | 69 | 32 | Yes |
| Grayson et al. (2018) | USA | Prospective | Cross sectional | TAK, GCA | ACR criteria 1990 or modified criteria for GCA | 115 (56; 26 TAK and 30 GCA) | 31* TAK, 69* GCA | 31 (TAK); 30 (GCA) | Yes |
| Henes et al. (2011) | Germany | Retrospective | Longitudinal | TAK, GCA | Clinical | 36 (10; 4 TAK and 6 GCA) | 48 (TAK); 63 (GCA) | 20 | Yes |
| Incerti et al. (2017) | Italy | Retrospective | Cross sectional | TAK | ACR criteria 1990 | 30 (30) | 43 | 13 | Yes |
| Lee et al. (2012) | South Korea | Retrospective | Longitudinal | TAK | ACR criteria 1990 (CTA or MRAinstead of conventional angiography) | 53 (38) with 13 (13) used in systematic review | 43* | 11 | Yes |
| Li et al. (2019) | China | Prospective | Cross sectional | TAK | ACR criteria 1990 (CTA or MRAinstead of conventional angiography) | 22 (71) | 34* total population; 34* PET-CT group | 16 total population; 23 PET-CT group | Yes |
| Martinez-Rodriguez et al. (2018) | Spain | Retrospective | Longitudinal | GCA, aortitis | ACR criteria 1990 | 74 (37) | 67* | 24 | Yes |
| Nielsen et al. (2018) | Denmark | Prospective | Longitudinal | GCA | Clinical, biochemical, biopsy,FDG results and ACR criteria 1990 | 48 (24) | 69* | 33 | Yes |
| Park et al. (2018) | South Korea | Prospective | Longitudinal | TAK | ACR criteria 1990 | 22 (11) | 47* | 0 | Yes |
| Quinn et al. (2018) | USA | Prospective | Cross sectional | TAK, GCA | ACR criteria 1990 or modifiedcriteria for GCA | 114 (65; 30 TAK and 35 GCA) | 33* TAK; 68* GCA | 33 (TAK); 20 (GCA) | Yes |
| Regola et al. (2020) | Italy | Retrospective | Longitudinal | GCA | ACR criteria 1990 or biopsyor FDG results | 30 (32) with 22 (11) used in a systematic review | 74 total population; PET-CT group not specified | 22 total population; r PET-CT group not specified | Yes |
| Rimland et al. (2020) | USA | Prospective | Cross sectional and longitudinal | TAK, GCA | ACR criteria 1990 ormodified criteria for GCA | 240 (112; 56 TAK and 56 GCA) | 34 (TAK); 71 (GCA) | 20 (TAK); 21 (GCA) | Yes |
| Sammel et al. (2020) | Australia | Prospective | Longitudinal | GCA | Biopsy and clinical follow-up for > 6 months | 36 (21) with 30 (15) included in systematic review | 73 total population; 71 for dual time-point | 33 | Yes |
| Santhosh et al. (2014) | India | Retrospective | Cross sectional | TAK | ACR criteria 1990 | 60 (51) with 43 (38) included in systematic review | Total population not reported; 30* patients at diagnosis | 25 | No |
| Schramm et al. (2019) | Germany | Retrospective | Cross sectional | TAK, GCA | ACR criteria 1990 and imaging | 80 (62) including 52 FDG-PET/CT scans without CT | Not reported | Not reported | Yes |
| Tezuka et al. (2012) | Japan | Retrospective | Cross sectional | TAK | ACR criteria 1990 and guideline for the management of vasculitissyndrome (Japanese circulationsociety 2008) | 39 (39) with 29 (29) included in a systematic review | 30 | 10 | Yes |
| Vitiello et al. (2018) | Italy | Retrospective | Longitudinal | GCA | ACR criteria 1990 | 24 (12) | 69* | 33 | Yes |
GCA, giant cell arteritis; LVV, large vessel vasculitis; TAK, Takayasu arteritis; * mean age is provided rather than median age.
* mean age is provided rather than median age