Table 1.
SNP | Chr | Position (hg38) | EA | OA | EAF | beta | se | P value | R2 | F statistic |
---|---|---|---|---|---|---|---|---|---|---|
Self-reported MVPA (based on a GWAS by Klimentidis et al. [23]) | ||||||||||
rs2942127 | 1 | 204450939 | G | A | 0.175 | 0.016 | 0.003 | 3.30E−08 | 0.00008 | 30.522 |
rs1974771 | 2 | 54051406 | G | A | 0.9 | -0.021 | 0.004 | 6.60E−09 | 0.00009 | 33.654 |
rs2114286 | 3 | 41152792 | A | G | 0.466 | − 0.012 | 0.002 | 3.30E−08 | 0.00008 | 30.501 |
rs877483 | 3 | 53812714 | T | C | 0.433 | 0.012 | 0.002 | 4.00E−08 | 0.00008 | 30.132 |
rs2035562 | 3 | 85007370 | A | G | 0.328 | − 0.014 | 0.002 | 3.90E−09 | 0.00009 | 34.687 |
rs1972763 | 4 | 158939411 | C | T | 0.342 | 0.013 | 0.002 | 3.30E−08 | 0.00008 | 30.526 |
rs77742115 | 5 | 18330315 | T | C | 0.862 | − 0.018 | 0.003 | 9.60E−09 | 0.00009 | 32.922 |
rs2854277 | 6 | 32660307 | C | T | 0.917 | 0.032 | 0.005 | 2.60E−10 | 0.00011 | 39.959 |
rs1186721 | 7 | 34934990 | G | A | 0.684 | − 0.013 | 0.002 | 4.40E−08 | 0.00008 | 29.984 |
rs921915 | 7 | 50188985 | T | C | 0.412 | − 0.014 | 0.002 | 5.70E−10 | 0.0001 | 38.436 |
rs1043595 | 7 | 128769958 | G | A | 0.717 | 0.014 | 0.002 | 4.30E−09 | 0.00009 | 34.481 |
rs7804463 | 7 | 133762898 | T | C | 0.53 | 0.015 | 0.002 | 1.20E−11 | 0.00012 | 45.987 |
rs2988004 | 9 | 37044391 | T | G | 0.558 | − 0.013 | 0.002 | 4.10E−09 | 0.00009 | 34.579 |
rs7326482 | 13 | 53463668 | G | T | 0.385 | − 0.013 | 0.002 | 1.60E−08 | 0.00008 | 31.915 |
rs10145335 | 14 | 98081411 | G | A | 0.749 | − 0.014 | 0.003 | 2.70E−08 | 0.00008 | 30.878 |
rs12912808 | 15 | 94748994 | C | T | 0.851 | 0.018 | 0.003 | 1.70E−08 | 0.00008 | 31.852 |
rs1921981 | 21 | 41050620 | G | A | 0.674 | 0.013 | 0.002 | 3.80E−08 | 0.00008 | 30.224 |
Accelerometer assessed average acceleration (based on a GWAS by Klimentidis et al. [23]) | ||||||||||
rs34517439 | 1 | 77984833 | C | A | 0.879 | 0.308 | 0.056 | 4.40E−08 | 0.00033 | 29.972 |
rs6775319 | 3 | 18717009 | A | T | 0.271 | 0.225 | 0.041 | 3.50E−08 | 0.00033 | 30.43 |
rs9293503 | 5 | 88653144 | T | C | 0.888 | 0.329 | 0.059 | 2.10E−08 | 0.00034 | 31.42 |
rs12522261 | 5 | 152675265 | G | A | 0.657 | 0.211 | 0.038 | 3.90E−08 | 0.00033 | 30.207 |
rs11012732 | 10 | 21541175 | A | G | 0.668 | 0.225 | 0.039 | 5.40E−09 | 0.00037 | 34.036 |
rs148193266 | 11 | 104657953 | A | C | 0.957 | − 0.51 | 0.092 | 3.10E−08 | 0.00034 | 30.67 |
rs59499656 | 18 | 43188344 | A | T | 0.656 | − 0.228 | 0.038 | 2.40E−09 | 0.00039 | 35.597 |
Fraction accelerations > 425 milli-gravities (based on a GWAS by Klimentidis et al. [23]) | ||||||||||
rs1856329 | 1 | 219766281 | A | C | 0.801 | 0.027 | 0.005 | 9.00E−08 | 0.00032 | 28.569 |
rs6433478 | 2 | 174376754 | T | C | 0.457 | − 0.024 | 0.004 | 1.20E−08 | 0.00036 | 32.465 |
rs62443625 | 7 | 39013531 | T | C | 0.767 | − 0.026 | 0.005 | 1.40E−07 | 0.00031 | 27.683 |
rs72633364 | 8 | 34329370 | G | A | 0.711 | − 0.023 | 0.005 | 4.10E−07 | 0.00028 | 25.635 |
rs4754194 | 11 | 107219461 | C | T | 0.773 | − 0.025 | 0.005 | 2.40E−07 | 0.00029 | 26.642 |
rs743580 | 15 | 74035775 | A | G | 0.51 | 0.025 | 0.004 | 1.30E−09 | 0.00041 | 36.764 |
rs1668835 | 18 | 24898988 | T | A | 0.688 | − 0.023 | 0.004 | 3.10E−07 | 0.00029 | 26.184 |
Sedentary behaviour (based on a GWAS by Doherty et al. [22]) | ||||||||||
rs61776614 | 1 | 2234967 | C | T | 0.925 | 0.05 | 0.009 | 3.90E−08 | 0.00033 | 30.182 |
rs1858242 | 3 | 68477984 | A | G | 0.259 | 0.031 | 0.005 | 3.80E−09 | 0.00038 | 34.745 |
rs26579 | 5 | 88689478 | G | C | 0.415 | 0.028 | 0.005 | 2.60E−09 | 0.00039 | 35.446 |
rs25981 | 5 | 107487207 | G | C | 0.531 | 0.028 | 0.005 | 2.70E−09 | 0.00039 | 35.366 |
rs6870096 | 5 | 152566250 | C | G | 0.321 | − 0.028 | 0.005 | 2.40E−08 | 0.00034 | 31.149 |
rs34858520 | 7 | 72258898 | A | G | 0.558 | 0.028 | 0.005 | 4.50E−09 | 0.00038 | 34.402 |
SNP single nucleotide polymorphism, Chr. chromosome, hg38 human genome assembly 38, EA effect allele, OA other allele, EAF effect allele frequency, beta beta estimate, se standard error, MVPA moderate to vigorous physical activity