Table 3.
Multivariate linear regression analysis: EAT and infarct size at baseline, 12 weeks and myocardial salvage index
| Predictors of endpoint | Infarct size (baseline), g B (95% CI) | p-value | Infarct size, g (12 weeks) B (95% CI) | p-value | Myocardial salvage index, g B (95% CI) | p-value |
|---|---|---|---|---|---|---|
| Anterior infarction | 7.17 ( – 5.18; 19.52) | 0.248 | 1.49 ( – 6.70; 9.68) | 0.715 | 0.02 ( – 0.08, 0.12) | 0.645 |
| TIMI-flow pre PCI* | 11.71 ( – 3.85; 27.26) | 0.136 | 6.69 ( – 3.63; 17.01) | 0.198 | – 0.02 ( – 0.14, 0.11) | 0.761 |
| TIMI-flow post PCI** | – 2.24 ( – 23.63; 19.15) | 0.834 | 3.25 ( – 10.94; 17.43) | 0.646 | – 0.11 ( – 0.28, – 0.06) | 0.214 |
| AHI*** | 3.07 ( – 9.13; 15.26) | 0.614 | 9.39 (1.20; 17.38) | 0.025 | – 0.20 ( – 0.30, – 0.10) | 0.001 |
| Epicardial adipose tissue, ml | 0.49 (0.09; 0.90) | 0.017 | 0.38 (0.11; 0.64) | 0.006 | 0.00 (0.00, 0.00) | 0.420 |
| Time to balloon, min | 0.11 ( – 0.61; 0.84) | 0.751 | 0.17 ( – 0.31; 0.65) | 0.477 | 0.00 ( – 0.01; 0.01) | 0.771 |
| Diabetes mellitus**** | 4.78 ( – 9.60; 19.16) | 0.506 | 4.86 ( – 4.68; 14.40) | 0.310 | – 0.06 ( – 0.17; 0.06) | 0.313 |
| Model summary***** | R2 = 0.478, F = 3.503 | R2 = 0.604, F = 5.828 | R2 = 0.524, F = 4.195 | |||
AHI apnea–hypopnea-index, EAT epicardial adipose tissue, B regression coefficient, CI confidence interval, TIMI Thrombolysis in Myocardial Infarction
*TIMI grade 0 vs TIMI grade 1
**TIMI grade 2 vs TIMI grade 3, PCI percutaneous coronary intervention
***AHI, stratified in ≥ 15/h and < 15/h
****Diabetes mellitus yes and no
*****All models controlled for age, sex, BMI and heart volume, significant p values (p < 0.05) marked in bold