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. 2021 Aug 13;48(12):4042–4053. doi: 10.1007/s00259-021-05501-1

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© The Author(s) 2021, corrected publication 2022

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Fig. 2 — Overview of the different immunohistochemical PSMA heterogeneity patterns. (A) shows homogenous strong and diffuse positivity. (B) depicts heterogenous PSMA positivity with focal weaker expression (arrowheads) in different components of the carcinoma, without negative areas. In (C), the circled carcinoma (continuous line) consists of approximately 30% (dotted line) negative areas, whereas in (D), roughly 80% of the marked invasive carcinoma shows negativity. Scale bar 5 mm