Table 5.

Impact of HMGA2 expression pattern on survival of PDAC patient

Staining parameter	Total number of patients	Number of deceased patients	Median survival ± SD (95% CI) in months	p-value
Intensity cytoplasm
Negative	11	9	15 ± 8.268 (0.000–31.205)
Weakly to strongly positive	86	69	15 ± 1.558 (11.946–18.054)	0.395
Number of cells with positively stained cytoplasm
≤ 80%	41	35	15 ± 2.403 (10.291–19.709)
> 80%	56	43	15 ± 3.453 (8.233–21.767)	0.687
Sum score cytoplasm
≤ 4	41	35	15 ± 2.403 (10.291–19.709)
> 4	56	43	15 ± 3.453 (8.233–21.767)	0.687
Staining intensity nuclei
Negative to weakly positive	72	55	16 ± 1.952 (12.174–19.826)
Moderately to strongly positive	25	23	8 ± 2.359 (3.375–12.625)	0.045
Number of cells with positively stained nucleus
≤ 80%	47	39	15 ± 1.217 (12.614–17.386)
> 80%	50	39	17 ± 6.635 (5.956–28.044)	0.591
Sum score nuclei
≤ 4	28	22	19 ± 2.531 (14.039–23.961)
> 4	69	56	15 ± 1.892 (11.293–18.707)	0.230

p-values were estimated by log-rank-test with p ≤ 0.05 considered as significant and represented in bold numbers

SD standard deviation, CI confidence interval