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. 2021 May 26;110(10):1625–1636. doi: 10.1007/s00392-021-01864-5

Table 3.

Medical treatment at enrollment and at hospital discharge

Overall population Women Men p value (sex) p value (visit)
Enrollment Discharge Enrollment Discharge Enrollment Discharge
Antihypertensive drug, all, n (%) 3,013 (89.9) 3,287 (98.1) 697 (90.2) 754 (97.5) 2,316 (89.8) 2,533 (98.2) 0.8  <0.001
ACE inhibitor, n (%) 1,902 (56.7) 2,299 (68.6) 405 (52.4) 506 (65.5) 1,497 (58.0) 1,793 (69.5)  <0.001  <0.001
AT1 receptor blocker, n (%) 685 (20.4) 742 (22.1) 167 (21.6) 181 (23.4) 518 (20.1) 561 (21.8) 0.2 0.09
Beta-blocker, n (%) 2,439 (72.8) 2,884 (86.0) 583 (75.4) 675 (87.3) 1,856 (72.0) 2,209 (85.7) 0.03  <0.001
Calcium channel blocker, n (%) 258 (7.7) 305 (9.1) 69 (8.9) 79 (10.2) 189 (7.3) 226 (8.8) 0.06 0.04
Loop diuretic, n (%) 625 (18.6) 723 (21.6) 166 (21.5) 196 (25.4) 459 (17.8) 527 (20.4)  <0.001 0.003
Diuretic, other (thiazides, potassium-sparing), n (%) 1,178 (35.1) 1,358 (40.5) 290 (37.5) 332 (42.9) 888 (34.4) 1,026 (39.8) 0.03  <0.001
Platelet aggregation inhibitor and/or anticoagulant, n (%) 2,794 (83.4) 3,237 (96.6) 634 (82.0) 745 (96.4) 2,160 (83.8) 2,492 (96.6) 0.2  <0.001
Platelet aggregation inhibitor ASA, n (%) 2,569 (76.6) 3,062 (91.3) 585 (75.7) 695 (89.9) 1,984 (76.9) 2,367 (91.8) 0.1  <0.001
Platelet aggregation inhibitor clopidogrel, n (%) 1,441 (43.0) 2,330 (69.5) 322 (41.7) 548 (70.9) 1,119 (43.4) 1,782 (69.1) 0.9  <0.001
Anticoagulant (heparin, vitamin K antagonist and/or NOAC), n (%) 548 (16.3) 695 (20.7) 128 (16.6) 169 (21.9) 420 (16.3) 526 (20.4) 0.4  <0.001
Statins, n (%) 2,282 (68.1) 2,817 (84.0) 512 (66.2) 633 (81.9) 1,770 (68.6) 2,184 (84.7) 0.03  <0.001

ACE, angiotensin-converting enzyme; ASA, acetylsalicylic acid; AT1, angiotensin II receptor type 1; HMG-CoA, 3-hydroxy-3-methylglutaryl-coenzyme A; NOAC, “non-vitamin K antagonist” oral anticoagulant