Table 2.
Initial conditions, epidemiological and vaccination parameter assumptions for the parsimonious SARS-CoV-2 transmission model.
Parameter | Baseline value | Source |
---|---|---|
Proportion of population vaccinated with AstraZeneca vaccine | 0.355 | Approximate proportion of England population vaccinated with the AstraZeneca vaccine by 17th May 2021 (from the National Immunisation Management Service) |
Proportion of population vaccinated with Pfizer/Moderna | 0.185 | Approximate proportion of England population vaccinated with Pfizer/Moderna vaccines by 17th May 2021 (from the National Immunisation Management Service) |
Proportion initially recovered | 0.26 | Mid-May England national average estimate of proportion recovered. From University of Warwick SARS-CoV-2 transmission model59. |
Proportion initially infected | 0.0009 | England central prevalence estimate (0.09%) from ONS infection study, 9th May–15th May 202167. |
Recovery rate (I- > R) | 0.4 days−1 | Estimate from Warwick model |
Rate from E- > I | 0.3 days−1 | Estimate from Warwick model |
R excluding immunity for England | [2.41,3.51] | Central estimate from Warwick model from roadmap Step 3 modelling36. Associated time intervals: [17th May–20th June 2021, 21st June 2021 onward] |
Maximum proportion of population vaccinated | 0.785 × 0.95 | Product of percentage aged 18+ (approximately 78.5%58) and assumed final coverage (95%) |
AstraZeneca/non-AstraZeneca vaccine ratio | 60%/40% | Assumed mixture as in57 |