Table 3.
Univariate and multivariable Cox regression analysis for outcomes.
| Outcomes | Non-adjusted | Adjusted | ||
|---|---|---|---|---|
| HR (95% CI) | p-Value | HR (95% CI) | p-Value | |
| Total patients | ||||
| ACM | ||||
| dNLR tertile | ||||
| 1 | 1 | 1 | ||
| 2 | 1.2 (0.8–2.0) | 0.368 | 1.283 (0.803–2.049) | 0.298 |
| 3 | 1.8 (1.2–2.8) | 0.006 | 1.763 (1.133–2.743) | 0.012 |
| CM | ||||
| dNLR tertile | ||||
| 1 | 1 | 1 | ||
| 2 | 1.6 (0.9–3.0) | 0.104 | 1.729 (0.945–3.164) | 0.076 |
| 3 | 2.1 (1.2–3.8) | 0.009 | 1.961 (1.083–3.550) | 0.026 |
| MACE | ||||
| dNLR tertile | ||||
| 1 | 1 | 1 | ||
| 2 | 1.0 (0.8–1.3) | 0.956 | 1.0 (0.8–1.3) | 0.777 |
| 3 | 1.1 (0.9–1.4) | 0.483 | 1.0 (0.7–1.3) | 0.864 |
| MACCE | ||||
| dNLR tertile | ||||
| 1 | 1 | 1 | ||
| 2 | 1.1 (0.9–1.4) | 0.36 | 1.1 (0.9–1.4) | 0.457 |
| 3 | 1.2 (0.9–1.4) | 0.165 | 1.0 (0.8–1.3) | 0.929 |
| ACS patients | ||||
| ACM | ||||
| dNLR tertile | ||||
| 1 | 1 | 1 | ||
| 2 | 1.180 (0.697–1.995) | 0.538 | 1.144 (0.676–1.938) | 0.616 |
| 3 | 1.643 (1.002–3.693) | 0.049 | 1.472 (0.894–2.423) | 0.129 |
| CM | ||||
| dNLR tertile | ||||
| 1 | 1 | 1 | ||
| 2 | 1.684 (0.866–3.274) | 0.124 | 1.559 (0.801–3.035) | 0.191 |
| 3 | 1.755 (0.903–3.411) | 0.097 | 1.462 (0.749–2.854) | 0.266 |
| MACE | ||||
| dNLR tertile | ||||
| 1 | 1 | 1 | ||
| 2 | 0.946 (0.713–1.255) | 0.700 | 0.939 (0.707–1.246) | 0.661 |
| 3 | 1.051 (0.797–1.387) | 0.723 | 1.033 (0.782–1.366) | 0.818 |
| MACCE | ||||
| dNLR tertile | ||||
| 1 | 1 | 1 | ||
| 2 | 1.070 (0.834–1.373) | 0.593 | 1.069 (0.833–1.373) | 0.457 |
| 3 | 1.196 (0.937–1.528) | 0.150 | 1.184 (0.926–1.515) | 0.178 |
| CCS patients | ||||
| ACM | ||||
| dNLR tertile | ||||
| 1 | 1 | 1 | ||
| 2 | 1.500 (0.558–4.030) | 0.421 | 1.395 (0.518–3.756) | 0.511 |
| 3 | 2.790 (1.165–6.683) | 0.006 | 2.385 (1.010–5.748) | 0.044 |
| CM | ||||
| dNLR tertile | ||||
| 1 | 1 | 1 | ||
| 2 | 1.479 (0.397, 5.511) | 0.560 | 1.403 (0.376–5.241) | 0.615 |
| 3 | 3.541 (1.154, 10.863) | 0.027 | 3.136 (1.015–9.690) | 0.047 |
| MACE | ||||
| dNLR tertile | ||||
| 1 | 1 | 1 | ||
| 2 | 1.081 (0.664–1.760) | 0.754 | 1.078 (0.662–1.757) | 0.762 |
| 3 | 1.162 (0.729–1.851) | 0.529 | 1.161 (0.727–1.855) | 0.532 |
| MACCE | ||||
| dNLR tertile | ||||
| 1 | 1 | 1 | ||
| 2 | 1.146 (0.754–1.742) | 0.523 | 1.142 (0.751–1.737) | 0.535 |
| 3 | 1.015 (0.668–1.542) | 0.944 | 1.007 (0.661–1.534) | 0.973 |
ACM, all-cause mortality; CM, cardiac mortality; MACE, major adverse cardiovascular events; MACCE, major adverse cardiovascular and cerebrovascular events; ACS, acute coronary syndrome; CCS, chronic coronary syndrome; dNLR, derived neutrophil-to-lymphocyte ratio.