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. 2021 Sep 17;12:750826. doi: 10.3389/fphar.2021.750826

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Copyright © 2021 Shu, Li, Cao, Li, Zhou, Ji and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of BBR on FXR^−/− mice. (A) The body weight and liver weight. (B) Serum ALT and AST levels. (C) Representative H&E staining images of liver sections (magnification 200×). (D) Liver TG content. (E) Serum TG, TC and LDL-c levels. (F) The mRNA expression of TNF-α and IL-6 in the liver. Data are presented as mean ± SEM (n = 6 per group).