Table 2:
Sample Characteristics
| Variable | Controls (n=53) | AD (n=78) | DLB (n=110) | Overall p-value | Post-hoc AD vs DLB |
|---|---|---|---|---|---|
| Age, y | 67.6 (10.0) | 79.7 (8.0) | 77.7 (7.6) | <.001 | .23 |
| Sex, %M | 30.8 | 44.9 | 72.7 | <.001 | <.001 |
| Education, y | 16.1 (2.2) | 15.2 (2.8) | 15.4 (2.8) | .17 | .91 |
| Hachinski | 0.5 (0.6) | 0.7 (0.8) | 0.9 (1.1) | .02 | .15 |
| FAQ | 0.1 (0.5) | 13.6 (8.5) | 17.0 (8.9) | <.001 | <.001 |
| NPI | 1.4 (1.9) | 7.6 (5.5) | 10.2 (6.5) | <.001 | .002 |
| UPDRS | 2.7 (3.5) | 5.4 (6.4) | 23.8 (16.4) | <.001 | <.001 |
| Hoehn & Yahr | 0.2 (0.5) | 0.3 (0.8) | 2.5 (1.1) | <.001 | <.001 |
| CDR | 0.0 (0.0) | 1.3 (0.7) | 1.6 (0.8) | <.001 | <.001 |
| CDR-SB | 0.1 (0.2) | 6.6 (3.6) | 8.7 (4.8) | <.001 | <.001 |
| Memory | 0.0 (0.0) | 1.3 (0.7) | 1.4 (0.7) | <.001 | .19 |
| Orientation | 0.0 (0.1) | 1.2 (0.8) | 1.3 (0.8) | <.001 | .02 |
| Judgment/Problem Solving | 0.1 (0.2) | 1.4 (0.7) | 1.8 (0.8) | <.001 | <.001 |
| Community Affairs | 0.0 (0.0) | 1.1 (0.7) | 1.5 (0.8) | <.001 | <.001 |
| Home/Hobbies | 0.0 (0.0) | 1.1 (0.8) | 1.6 (0.9) | <.001 | <.001 |
| Personal Care | 0.0 (0.0) | 0.5 (0.7) | 1.2 (1.0) | <.001 | <.001 |
Mean (SD) or %
KEY: AD=Alzheimer’s disease; DLB=Dementia with Lewy bodies; FAQ=Functional Activities Questionnaire; NPI=Neuropsychiatric Inventory; UPDRS=Unified Parkinson’s Disease Rating Scale; CDR=Clinical Dementia Rating; CDR-SB=CDR Sum of boxes
Bold indicates post-hoc significance for AD vs DLB after correction for multiple comparisons (corrected p-value<.003)