Table 5:

Comparison of LBD-MOD Autonomic Feature Checklist Constructs between Cognitively Normal Controls, Alzheimer Disease, and Dementia with Lewy Bodies

Variable	Controls (n=53)	AD (n=78)	DLB (n=110)	Overall p-value	Post-hoc AD vs DLB
Dribbles saliva, %	0.0	0.0	18.4	<.001	<.001
Difficulty swallowing, %	2.0	1.4	17.3	<.001	.001
Increased interest in sex, %	5.9	5.5	14.3	.09	.63
Decreased interest in sex, %	15.7	26.0	33.7	.06	.28
Problems with sexual performance, %	31.4	19.2	55.1	<.001	<.001
Weight loss (not due to dieting), %	0.0	26.0	30.6	<.001	.51
Change in sense of taste, %	7.8	15.1	26.5	.01	.07
Change in sense of smell, %	5.9	11.0	23.5	.008	.04
Excessive sweating, %	5.9	8.2	7.1	.88	.79
Cold intolerance, %	21.6	38.4	58.2	<.001	.01
Heat intolerance, %	9.8	13.7	21.4	.15	.19
Double vision, %	3.9	1.4	13.3	.007	.005
Difficulty digesting food, %	3.9	9.6	15.3	.09	.27
Constipation, %	5.9	28.8	40.8	<.001	.10
Obstipation, %	7.8	17.8	35.7	<.001	.01
Bowel incontinence, %	9.8	11.0	22.4	.05	.05
Incomplete bladder emptying, %	11.8	17.8	34.7	.003	.01
Weak urine stream, %	5.9	8.2	21.4	.008	.02
Urinary Frequency, %	13.7	28.8	46.9	<.001	.02
Urinary Incontinence, %	9.8	28.8	44.9	<.001	.03
Lightheaded/Dizzy when standing, %	9.8	23.3	49.0	<.001	.001
Lightheaded when prolonged standing, %	7.8	9.6	32.7	<.001	<.001
Fainting, %	2.0	6.8	5.1	.46	.63
Total Features, Mean (SD)	1.9 (2.7)	3.6 (2.4)	6.7 (3.6)	<.001	<.001

Mean (SD) or %

KEY: AD=Alzheimer’s disease; DLB=Dementia with Lewy bodies

Bold indicates post-hoc significance for AD vs DLB after correction for multiple comparisons (corrected p-value<.002)