Table 3.
Immunohistochemical staining results for the FIGO grade 3 component with diffusely aberrant ß-catenin expression
| Case | CDX2 | PAX8 | ER | AE1/AE3 | CK7 | CK20 | Syn | Chr | INSM1 | p63 | p53 | p16 | PMS2 | MSH6 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | >50% | N | N | P | P | N | 30% | 5% | N | N | WT | patchy | R | R |
| 2 | >50% | N | N | P | P | 2% | 40% | 10% | N | 15% | WT | patchy | R | R |
| 3 | >50% | N | N | P | P | N | 20% | 2% | 2% | N | WT | patchy | R | R |
| 4 | 40% | N | N | P | P | N | 40% | 5% | N | N | WT | patchy | R | R |
| 5 | 40% | N | N | P | P | N | 60% | 10% | N | 5% | WT | patchy | R | R |
Abbreviations: Chr: chromogranin; N: negative; P: positive (diffuse); R: retained; Syn: synaptophysin; WT: wild-type staining pattern.