Table 3.

Spearman correlations between changes from baseline to week 16 in P-SIM item scores and other clinician- and patient-reported outcomes

P-SIM item	Spearman correlation coefficient for changes from baseline to week 16
	PASI total score (n = 698)	DLQI total score (n = 698)	DLQI item 1 score (n = 696)	IGA score (n = 698)	PGAP scorea (n = 314)
Item 1—itching	0.42	0.61*	0.74*	0.48	0.72*
Item 2—redness	0.45	0.61*	0.68*	0.50	0.74*
Item 3—skin pain	0.44	0.60*	0.69*	0.46	0.68*
Item 4—burning	0.44	0.61*	0.70*	0.48	0.69*
Item 5—scaling	0.49	0.61*	0.66*	0.53*	0.73*
Item 6—cracking	0.43	0.60*	0.65*	0.47	0.68*
Item 7—dryness	0.44	0.60*	0.68*	0.49	0.75*
Item 8—irritation	0.44	0.63*	0.70*	0.49	0.73*
Item 9—sensitivity	0.44	0.61*	0.68*	0.48	0.70*
Item 10—lesions	0.45	0.62*	0.65*	0.49	0.72*
Item 11—thickening	0.44	0.61*	0.64*	0.49	0.71*
Item 12—fatigue	0.38	0.61*	0.54*	0.44	0.60*
Item 13—embarrassment	0.38	0.69*	0.56*	0.46	0.61*
Item 14—choice of clothing	0.38	0.68*	0.50	0.46	0.59*

Data were pooled from BE VIVID and BE READY

DLQI Dermatology Life Quality Index, IGA Investigator’s Global Assessment, PASI Psoriasis Area and Severity Index, PGAP Patient Global Assessment of Psoriasis, P-SIM Psoriasis Symptoms and Impacts Measure

*Correlation coefficients that are strong (> 0.50)

^aChanges from baseline to week 12 were used for PGAP as a result of substantial amounts of missing data at week 16