Table 5.
Proportion of patients with PGA score by visit (per protocol population)
| PGA score by visit | Clobetasol propionate 0.025% cream | Clobetasol propionate 0.05% cream (N = 13) |
|
|---|---|---|---|
| Formulation 5 (N = 18) |
Formulation 13 (N = 19) |
||
| Baseline visit | |||
| 0 | 0 | 0 | 0 |
| 1 | 0 | 0 | 0 |
| 2 | 0 | 0 | 0 |
| 3 | 11 (61.1) | 12 (63.2) | 7 (53.8) |
| 4 | 7 (38.9) | 7 (36.8) | 6 (46.2) |
| Mean (SD) | 3.4 (0.50) | 3.4 (0.50) | 3.5 (0.52) |
| Success | 0 | 0 | 0 |
| Visit 3 (day 7) | |||
| 0 | 0 | 0 | 0 |
| 1 | 0 | 0 | 0 |
| 2 | 0 | 3 (15.8) | 1 (7.7) |
| 3 | 14 (77.8) | 13 (68.4) | 9 (69.2) |
| 4 | 4 (22.2) | 3 (15.8) | 3 (23.1) |
| Mean (SD) | 3.2 (0.43) | 3.0 (0.58) | 3.2 (0.55) |
| Success | 0 | 0 | 0 |
| Visit 4 (day 14) | |||
| 0 | 0 | 0 | 0 |
| 1 | 0 | 1 (5.3) | 1 (7.7) |
| 2 | 8 (44.4) | 9 (47.4) | 5 (38.5) |
| 3 | 10 (55.6) | 7 (36.8) | 7 (53.8) |
| 4 | 0 | 2 (10.5) | 0 |
| Mean (SD) | 2.6 (0.51) | 2.5 (0.77) | 2.5 (0.66) |
| Successa | 0 | 1 (5.3) | 1 (7.7) |
| Visit 5 (day 21) | |||
| 0 | 0 | 1 (5.3) | 1 (7.7) |
| 1 | 2 (11.1) | 1 (5.3) | 0 |
| 2 | 13 (72.2) | 13 (68.4) | 10 (76.9) |
| 3 | 3 (16.7) | 4 (21.1) | 2 (15.4) |
| 4 | 0 | 0 | 0 |
| Mean (SD) | 2.1 (0.54) | 2.1 (0.71) | 2.0 (0.71) |
| Successb | 2 (11.1) | 2 (10.5) | 1 (7.7) |
| Visit 6 (day 28) | |||
| 0 | 0 | 1 (5.3) | 1 (7.7) |
| 1 | 7 (38.9) | 6 (31.6) | 3 (23.1) |
| 2 | 11 (61.1) | 10 (52.6) | 8 (61.5) |
| 3 | 0 | 2 (10.5) | 1 (7.7) |
| 4 | 0 | 0 | 0 |
| Mean (SD) | 1.6 (0.50) | 1.7 (0.75) | 1.7 (0.75) |
| Successc | 7 (38.9) | 7 (36.8) | 4 (30.8) |
All values are presented as n (%) unless specified. SD, standard deviation.
0, clear; 1, almost clear; 2, mild; 3, moderate; 4, moderate to severe.
ap value 0.5245
bp value 0.9477
cp value 0.8934