Table 2.

List of tested inhibitors, drug class, and reported effects on CYP3A7.

Compound	MW (g/mol)	Drug class	Known CYP3A7 effects
Boceprevir	519.7	HCV protease inhibitor	N/A
Danoprevir	731.8	HCV protease inhibitor	N/A
Dasabuvir	493.6	HCV NNRTI	N/A
Glecaprevir	838.9	HCV protease inhibitor	N/A
Grazoprevir	766.9	HCV protease inhibitor	N/A
Ledipasvir	889	HCV phosphoprotein inhibitor	N/A
Lomibuvir	445.6	HCV NNRTI	N/A
Ombitasvir	894.1	HCV phosphoprotein inhibitor	N/A
Simeprevir	749.9	HCV protease inhibitor	N/A
Telaprevir	679.9	HCV protease inhibitor	N/A
Amprenavir	505.6	HIV protease inhibitor	Inhibitor
Ataznavir	704.9	HIV protease inhibitor	N/A
Darunavir	547.7	HIV protease inhibitor	N/A
Lopinavir	628.8	HIV protease inhibitor	Inhibitor
Nelfinavir	663.9	HIV protease inhibitor	Inhibitor
Ritonavir	720.9	HIV protease inhibitor, pharmacoenhancer	Inhibitor

NNRTI: non-nucleoside reverse transcriptase inhibitor.