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. 2021 Jul 17;6(10):2594–2603. doi: 10.1016/j.ekir.2021.07.011

Table 5.

Risk factors of death at day 30 after transjugular kidney biopsy

Transjugular kidney biopsy Univariate
P value Multivariable
P value
OR, 95%CI OR, 95%CI
Major bleeding after biopsy 2.30 (1.42–4.06) 0.001 1.77 (1.00–3.14) 0.05
Age (per 1 quartile) 1.35 (1.13–1.60) 0.001 1.44 (1.16–1.80) 0.001
Sex (male) 1.57 (1.05–2.32) 0.03 1.20 (0.78–1.84) 0.40
Charlson Comorbidity Index (per 1 quartile) 1.37 (1.15–1.64) <0.0001 0.77 (0.59–1.01) 0.06
Frailty index (per 1 quartile) 1.41 (1.18–1.69) <0.0001 1.08 (0.87–1.34) 0.50
History of cardiovascular and metabolic diseases
 Hypertension 0.62 (0.43–0.90) 0.01 0.50 (0.32–0.77) 0.002
 Diabetes mellitus 0.72 (0.47–1.10) 0.12 0.57 (0.34–0.96) 0.04
 Obesity 1.22 (0.80–1.85) 0.36 1.63 (1.01–2.62) 0.05
 Heart failure 2.87 (1.97–4.18) <0.0001 2.71 (1.70–4.33) <0.0001
 Valve disease 1.36 (0.70–2.62) 0.36 0.74 (0.36–1.53) 0.42
 Coronary artery disease 1.38 (0.90–2.12) 0.14 0.98 (0.55–1.76) 0.96
 Vascular disease 1.34 (0.84–2.12) 0.22 1.42 (0.77–2.62) 0.26
 Atrial fibrillation 2.00 (1.29–3.12) 0.002 1.17 (0.69–2.00) 0.55
 Stroke 0.63 (0.20–1.99) 0.43 0.66 (0.20–2.21) 0.50
 Smoker 1.12 (0.65–1.90) 0.69 0.82 (0.46–1.48) 0.52
 Dyslipidemia 0.65 (0.41–1.02) 0.06 0.72 (0.43–1.22) 0.22
History of other comorbid conditions
 Denutrition 1.80 (1.13–2.86) 0.01 0.98 (0.58–1.64) 0.93
 Alcohol-related disease 3.31 (2.24–4.89) <0.0001 1.37 (0.80–2.34) 0.25
 Lung disease 1.58 (1.00–2.49) 0.05 1.04 (0.63–1.74) 0.87
 Liver disease 4.61 (3.19–6.65) <0.0001 4.25 (2.54–7.13) <0.0001
 Anaemia 1.45 (1.00–2.09) 0.05 0.84 (0.55–1.31) 0.45
 Thrombocytopenia 1.31 (0.80–2.16) 0.28 0.63 (0.36–1.09) 0.10
 History of cancer 2.09 (1.44–3.01) <0.0001 1.97 (1.23–3.07) 0.003
Renal presentations
 Abnormal renal function 0.70 (0.48–1.02) 0.06 0.65 (0.43–1.00) 0.05
 Acute renal injury 4.53 (2.90–7.06) <0.0001 3.39 (2.05–5.61) <0.0001
 Glomerular disease 0.57 (0.37–0.89) 0.01 1.01 (0.62–1.63) 0.97
 Vascular or hypertensive disease 0.40 (0.16–0.99) 0.05 0.64 (0.25–1.67) 0.36
 Diabetic kidney disease 0.49 (0.20–1.19) 0.12 0.63 (0.23–1.72) 0.37
 Autoimmune disease 0.47 (0.20–1.06) 0.07 0.89 (0.37–2.15) 0.80
 Vasculitis 0.35 (0.05–2.54) 0.30 0.30 (0.04–2.26) 0.24
 Hematological-related renal disease 0.39 (0.05–2.83) 0.35 0.33 (0.04–2.46) 0.28
 Thrombotic microangiopathy 0.89 (0.36–2.18) 0.79 1.13 (0.43–2.96) 0.80
 Amyloidosis 4.16 (1.47–11.78) 0.007 2.95 (0.98–8.87) 0.06
 Other diagnoses 0.79 (0.11–5.76) 0.82 0.78 (0.10–5.99) 0.81

CI, confidence interval; OR, odds ratio.