Table 6.
Risk factors of death at day 30 after percutaneous kidney biopsy
| Percutaneous kidney biopsy | Univariate |
p value | Multivariable |
p value |
|---|---|---|---|---|
| OR, 95%CI | OR, 95%CI | |||
| Major bleeding after biopsy | 3.13 (2.53–3.88) | <0.0001 | 1.80 (1.43–2.28) | <0.0001 |
| Age (per 1 quartile) | 1.96 (1.81–2.14) | <0.0001 | 1.63 (1.47–1.80) | <0.0001 |
| Gender (male) | 1.40 (1.19–1.62) | <0.0001 | 1.21 (1.01–1.43) | 0.04 |
| Charlson comorbidity index (per 1 quartile) | 1.79 (1.66–1.92) | <0.0001 | 1.05 (0.94–1.16) | 0.41 |
| Frailty index (per 1 quartile) | 1.67 (1.55–1.79) | <0.0001 | 1.11 (1.02–1.21) | 0.02 |
| History of cardiovascular and metabolic diseases | ||||
| Hypertension | 1.25 (1.06–1.46) | 0.006 | 0.84 (0.70–1.00) | 0.05 |
| Diabetes mellitus | 1.10 (0.92–1.32) | 0.28 | 0.76 (0.61–0.94) | 0.01 |
| Obesity | 1.07 (0.87–1.31) | 0.55 | 0.97 (0.78–1.21) | 0.78 |
| Heart failure | 3.86 (3.28–4.56) | <0.0001 | 2.18 (1.78–2.66) | <0.0001 |
| Valve disease | 1.96 (1.49–2.58) | <0.0001 | 0.76 (0.56–1.03) | 0.08 |
| Coronary artery disease | 2.61 (2.18–3.13) | <0.0001 | 1.46 (1.17–1.83) | 0.001 |
| Vascular disease | 1.75 (1.43–2.14) | <0.0001 | 0.92 (0.73–1.17) | 0.51 |
| Atrial fibrillation | 2.85 (2.36–3.43) | <0.0001 | 1.08 (0.87–1.34) | 0.48 |
| Stroke | 1.93 (1.29–2.89) | 0.001 | 1.15 (0.75–1.75) | 0.53 |
| Smoker | 1.36 (1.08–1.70) | 0.008 | 1.02 (0.80–1.32) | 0.86 |
| Dyslipidemia | 1.22 (1.01–1.46) | 0.04 | 0.86 (0.69–1.05) | 0.14 |
| History of other comorbid conditions | ||||
| Denutrition | 2.82 (2.34–3.40) | <0.0001 | 1.32 (1.07–1.61) | 0.008 |
| Alcohol-related disease | 2.43 (1.97–3.01) | <0.0001 | 1.22 (0.93–1.60) | 0.14 |
| Lung disease | 2.34 (1.94–2.82) | <0.0001 | 1.22 (0.99–1.50) | 0.06 |
| Liver disease | 3.56 (2.94–4.30) | <0.0001 | 2.49 (1.96–3.17) | <0.0001 |
| Anaemia | 2.18 (1.86–2.54) | <0.0001 | 1.00 (0.84–1.21) | 0.97 |
| Thrombocytopenia | 1.56 (1.22–1.99) | <0.0001 | 0.74 (0.57–0.97) | 0.03 |
| History of cancer | 4.38 (3.75–5.12) | <0.0001 | 2.78 (2.32–3.34) | <0.0001 |
| Renal presentations | ||||
| Abnormal renal function | 0.98 (0.83–1.15) | 0.76 | 0.62 (0.52–0.75) | <0.0001 |
| Acute renal injury | 3.29 (2.82–3.86) | <0.0001 | 2.05 (1.70–2.46) | <0.0001 |
| Glomerular disease | 0.47 (0.38–0.57) | <0.0001 | 0.72 (0.59–0.89) | 0.002 |
| Vascular or hypertensive disease | 0.41 (0.27–0.61) | <0.0001 | 0.49 (0.32–0.74) | 0.001 |
| Diabetic kidney disease | 0.66 (0.47–0.94) | 0.02 | 0.72 (0.49–1.07) | 0.10 |
| Autoimmune disease | 0.67 (0.46–0.98) | 0.04 | 1.08 (0.73–1.59) | 0.71 |
| Vasculitis | 1.40 (1.00–1.96) | 0.05 | 1.25 (0.88–1.79) | 0.21 |
| Hematological-related renal disease | 1.37 (0.93–2.02) | 0.11 | 0.67 (0.45–1.01) | 0.06 |
| Thrombotic microangiopathy | 1.44 (0.91–2.28) | 0.12 | 1.01 (0.62–1.63) | 0.98 |
| Amyloidosis | 4.59 (2.56–8.24) | <0.0001 | 2.49 (1.35–4.59) | 0.004 |
| Other diagnoses | 0.61 (0.25–1.47) | 0.27 | 0.37 (0.15–0.90) | 0.03 |
CI, confidence interval; OR, odds ratio.