Table 1.
Non-coding RNAs regulating EndMT in atherosclerosis.
| Non-coding RNAs | Targets | Regulation | Models | Year | Reference |
|---|---|---|---|---|---|
| miR-449a | AdipoR2 | upregulation | ApoE−/− diabetic mice Human carotid atherosclerotic plaque HUVECs |
2019 | (76) |
| miR-374b | MAPK7 | upregulation | Human coronary arteries Pigs HUVECs |
2019 | (77) |
| miR-122 | NPAS3 | upregulation | ApoE−/− mice HAECs HUVECs |
2021 | (78) |
| H19 | TET1/TGFβR2/TSP1 | upregulation | H19 KO mice Primary mouse pulmonary endothelial cells HAECs HUVECs |
2010 | (83) |
| MALAT1 | Wnt/β-catein | upregulation | ApoE−/− mice HUVECs |
2019 | (85) |
| LIC00657 | miR-30c-5p/Wnt7b/β-catenin | upregulation | Atherosclerosis patients serum HUVECs |
2020 | (86) |
| LncRNA ZFAS1 | miR-150-5P/Notch3 | upregulation | ApoE−/− mice HUVECs | 2021 | (89) |
List of non-coding RNAs regulating EndMT associated with atherosclerosis including miRNA and lncRNAs. AdipoR2, Adiponectin receptor 2; MAPK7, Mitogen-activated protein kinase 7; NPAS3, Neuronal PAS Domain Protein 3; TET1, Tet Methylcytosine Dioxygenase 1; TGFβR2, TGF-βreceptor 2; TSP1, Thrombospondin 1; MALAT1, Metastasis-associated lung adenocarcinoma transcript 1; HUVECs, Human umbilical vein endothelial cells; HAECs, Human Aortic Endothelial Cells.