Table 2.
The difference of dynamic functional connectivity variability in default mode network across three groups.
Region(aal) | Peak MNI coordinate | F/t | Cluster number | ||
---|---|---|---|---|---|
x | y | z | |||
Anterior default mode network | |||||
ANCOVA | |||||
R parahippocampal gyrus | 21 | −18 | −30 | 6.3284 | 20 |
R inferior frontal gyrus | 36 | 24 | −24 | 7.0609 | 42 |
B anterior cingulum gyrus | −6 | 39 | 3 | 8.9345 | 22 |
L caudate | −9 | 6 | −3 | 7.232 | 38 |
R angular gyrus/superior temporal gyrus | 60 | −51 | 21 | 6.6394 | 79 |
R superior frontal gyrus | 21 | 39 | 27 | 7.4796 | 40 |
L superior frontal gyrus | −21 | 33 | 54 | 7.2538 | 21 |
aMCI vs. HC | |||||
R angular gyrus | 42 | −51 | 24 | −3.0653 | 18 |
R superior frontal gyrus | 24 | 39 | 33 | −3.6477 | 18 |
Posterior default mode network | |||||
ANCOVA | |||||
R middle temporal gyrus | 66 | −45 | −3 | 6.9386 | 21 |
SCD vs. HC | |||||
R middle temporal gyrus | 66 | −45 | 0 | −3.1797 | 10 |
Salience network | |||||
ANCOVA | |||||
R Hippocampus | 39 | −27 | 6 | 3.8555 | 20 |
R superior temporal gyrus | 51 | −24 | 6 | 3.1027 | 34 |
L hippocampus | −18 | −18 | −15 | 6.3901 | 49 |
R inferior frontal gyrus | 45 | 39 | −6 | 7.1029 | 47 |
L insula/putamen | −45 | 12 | 3 | 11.4039 | 252 |
L superior temporal gyrus | −48 | −39 | 18 | 6.4033 | 57 |
R inferior frontal gyrus | 45 | 15 | 15 | 6.6237 | 28 |
SCD vs. HC | |||||
L putamen | −30 | −3 | −3 | 3.6342 | 15 |
L insula | −45 | 12 | 3 | 4.1688 | 53 |
aMCI vs. HC | |||||
L putamen | −27 | 12 | −3 | 4.0464 | 11 |
Executive control network | |||||
ANCOVA | |||||
R middle frontal gyrus | 33 | 54 | 9 | 7.1346 | 38 |
L inferior frontal gyrus | −39 | 9 | 24 | 6.3027 | 59 |
R middle frontal gyrus | 45 | 36 | 21 | 5.0147 | 64 |
L middle frontal gyrus | −42 | 45 | 18 | 7.732 | 39 |
R inferior parietal lobule | 54 | −42 | 42 | 8.0083 | 32 |
SCD vs. HC | |||||
L middle frontal gyrus | −48 | 42 | 21 | 3.8698 | 22 |
aMCI vs. HC | |||||
R middle frontal gyrus | 30 | 57 | 6 | −3.3649 | 11 |
L inferior frontal gyrus | −36 | 15 | 15 | 3.7362 | 14 |
The x, y, z coordinates are the primary peak locations in the MNI space. Cluster size > 19 voxels in ANCOVA analysis, p < 0.05; Cluster size > 10 voxels in post hoc test, p < 0.05, TFCE-FWE corrected; L, left; R, right; B, bilateral; aMCI, amnestic mild cognitive impairment; SCD, subjective cognitive decline; HC, healthy control.