TABLE 2.

A list of histone lysine methyltransferase inhibitors under different phases of clinical trial and their indication.

Histone lysine methyltransferase inhibitors
Classification	Compounds	Structure	Clinical stage	References
G9a (H3K9)	BIX-01294		Preclinical	Deng et al. (2020a)
		UNC0638		Preclinical	Nualkaew et al. (2020)
EZH2 (H3K27)	EI1		Preclinical	Fioravanti et al. (2018)
	CPI-1205		Clinical	Gulati et al. (2018)
		EPZ6438		Clinical	Zhou et al. (2020)
	SMYD2 (H3K36)	AZ-505		Preclinical	de Grass et al. (2014)
		LLY-507		Preclinical	Kukita et al. (2019)
DOT1L (H3K79)	SYC-522		Preclinical	Liu et al. (2014)
		EPZ-5676		Clinical